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PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting

Vein grafting is a frequently used surgical intervention for cardiac revascularization. However, vein grafts display regions with intraplaque (IP) angiogenesis, which promotes atherogenesis and formation of unstable plaques. Graft neovessels are mainly composed of endothelial cells (ECs) that largel...

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Detalles Bibliográficos
Autores principales:	Perrotta, Paola, de Vries, Margreet R., Peeters, Bart, Guns, Pieter-Jan, De Meyer, Guido R. Y., Quax, Paul H. A., Martinet, Wim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2021
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813728/ https://www.ncbi.nlm.nih.gov/pubmed/34432198 http://dx.doi.org/10.1007/s10456-021-09816-3

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