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Escape From Cisplatin-Induced Senescence of Hypoxic Lung Cancer Cells Can Be Overcome by Hydroxychloroquine

Chemotherapy is the commonly used treatment for advanced lung cancer. However, it produces side effects such as the development of chemoresistance. A possible responsible mechanism may be therapy-induced senescence (TIS). TIS cells display increased senescence-associated β-galactosidase (SA-β-gal) a...

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Detalles Bibliográficos
Autores principales: Olszewska, Aleksandra, Borkowska, Agata, Granica, Monika, Karolczak, Justyna, Zglinicki, Bartosz, Kieda, Claudine, Was, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813758/
https://www.ncbi.nlm.nih.gov/pubmed/35127467
http://dx.doi.org/10.3389/fonc.2021.738385