Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Docosahexaenoic Acid Supplementation

Repeated short-term intranasal instillation of lupus-prone mice with crystalline silica (cSiO(2)) induces inflammatory gene expression and ectopic lymphoid neogenesis in the lung, leading to early onset of systemic autoimmunity and rapid progression to glomerulonephritis. These responses are suppres...

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Detalles Bibliográficos
Autores principales: Rajasinghe, Lichchavi D., Bates, Melissa A., Benninghoff, Abby D., Wierenga, Kathryn A., Harkema, Jack R., Pestka, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813772/
https://www.ncbi.nlm.nih.gov/pubmed/35126352
http://dx.doi.org/10.3389/fimmu.2021.781446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813772/
https://www.ncbi.nlm.nih.gov/pubmed/35126352
http://dx.doi.org/10.3389/fimmu.2021.781446

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