Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling

BACKGROUND AND OBJECTIVE: While one in five children in the USA are now obese, and more than three-quarters receive at least one drug during childhood, there is limited dosing guidance for this vulnerable patient population. Physiologically based pharmacokinetic modeling can bridge the gap in the un...

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Detalles Bibliográficos
Autores principales: Gerhart, Jacqueline G., Carreño, Fernando O., Edginton, Andrea N., Sinha, Jaydeep, Perrin, Eliana M., Kumar, Karan R., Rikhi, Aruna, Hornik, Christoph P., Harris, Vincent, Ganguly, Samit, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813791/
https://www.ncbi.nlm.nih.gov/pubmed/34617262
http://dx.doi.org/10.1007/s40262-021-01072-4

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