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Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells

Embryonic stem cells (ES) are a valuable source of endothelial cells. By co-culturing ES cells with the stromal PA6 cells, the endothelial commitment can be achieved by adding exogenous FGF2 or BMP4. In this work, the molecular pathways that direct the differentiation of ES cells toward endothelium...

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Detalles Bibliográficos
Autores principales: Gualandris, Anna, Noghero, Alessio, Cora’, Davide, Astanina, Elena, Arese, Marco, Bussolino, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813801/
https://www.ncbi.nlm.nih.gov/pubmed/34478025
http://dx.doi.org/10.1007/s10456-021-09815-4

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