Cargando…

The importance of enhancer methylation for epigenetic regulation of tumorigenesis in squamous lung cancer

Lung squamous cell carcinoma (LUSC) is a subtype of non-small cell lung cancer (NSCLC). LUSC occurs at the bronchi, shows a squamous appearance, and often occurs in smokers. To determine the epigenetic regulatory mechanisms of tumorigenesis, we performed a genome-wide analysis of DNA methylation in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cho, Jae-Won, Shim, Hyo Sup, Lee, Chang Young, Park, Seong Yong, Hong, Min Hee, Lee, Insuk, Kim, Hye Ryun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813945/ https://www.ncbi.nlm.nih.gov/pubmed/34987166 http://dx.doi.org/10.1038/s12276-021-00718-4

Ejemplares similares

Genome-wide identification of differentially methylated promoters and enhancers associated with response to anti-PD-1 therapy in non-small cell lung cancer
por: Cho, Jae-Won, et al.
Publicado: (2020)

Dysregulation of T(FH)-B-T(RM) lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer
por: Cho, Jae-Won, et al.
Publicado: (2021)

Overexpression of PVR and PD-L1 and its association with prognosis in surgically resected squamous cell lung carcinoma
por: Lee, Jii Bum, et al.
Publicado: (2021)

Publisher Correction: Overexpression of PVR and PD‑L1 and its association with prognosis in surgically resected squamous cell lung carcinoma
por: Lee, Jii Bum, et al.
Publicado: (2021)

Clinical outcomes in ALK-rearranged lung adenocarcinomas according to ALK fusion variants
por: Cha, Yoon Jin, et al.
Publicado: (2016)

Screening of ROS1 Rearrangements in Lung Adenocarcinoma by Immunohistochemistry and Comparison with ALK Rearrangements
por: Cha, Yoon Jin, et al.
Publicado: (2014)

Epigenetic Inactivation of Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 2 in Lung Cancer and Its Role in Tumorigenesis
por: Hwang, Jung-Ah, et al.
Publicado: (2013)

Comprehensive analysis of the characteristics and treatment outcomes of patients with non-small cell lung cancer treated with anti-PD-1 therapy in real-world practice
por: Ahn, Beung-Chul, et al.
Publicado: (2019)

Genetic Analysis and Operative Outcomes in Patients with Oncogene-Driven Advanced NSCLC Treated with Cytoreductive Surgery as a Component of Local Consolidative Therapy
por: Park, Byung Jo, et al.
Publicado: (2021)

The feasibility and safety of radical esophagectomy in patients receiving neoadjuvant chemoradiotherapy with pembrolizumab for esophageal squamous cell carcinoma
por: Park, Seong Yong, et al.
Publicado: (2020)

Concordance of programmed death-ligand 1 expression between primary and metastatic non-small cell lung cancer by immunohistochemistry and RNA in situ hybridization
por: Kim, Hye Ryun, et al.
Publicado: (2017)

Integrated evaluation of clinical, pathological and radiological prognostic factors in squamous cell carcinoma of the lung
por: Gu, Kyowon, et al.
Publicado: (2019)

Comprehensive analyses of immunodynamics and immunoreactivity in response to treatment in ALK-positive non-small-cell lung cancer
por: Pyo, Kyoung-Ho, et al.
Publicado: (2020)

Systems biology analysis identifies TNFRSF9 as a functional marker of tumor-infiltrating regulatory T-cell enabling clinical outcome prediction in lung cancer
por: Cho, Jae-Won, et al.
Publicado: (2021)

Prognostic role of extracellular vesicles in squamous cell carcinoma of the lung
por: An, Hyo Jung, et al.
Publicado: (2020)

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells
por: Boo, Hye-Jin, et al.
Publicado: (2016)

Predicting treatment outcomes using (18)F-FDG PET biomarkers in patients with non-small-cell lung cancer receiving chemoimmunotherapy
por: Kim, Chang Gon, et al.
Publicado: (2022)

High CD3 and ICOS and low TIM-3 expression predict favourable survival in resected oesophageal squamous cell carcinoma
por: Hong, Min Hee, et al.
Publicado: (2019)

Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis
por: Kim, Eunji, et al.
Publicado: (2023)

Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma
por: Fujii, Shinsuke, et al.
Publicado: (2016)

Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis
por: Lee, Hyun-Sung, et al.
Publicado: (2014)

Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer
por: Kim, Kyungsoo, et al.
Publicado: (2020)

Colonic Lymphangiomatosis Resolved after Excisional Biopsy
por: Lee, Young Soo, et al.
Publicado: (2015)

A phase II study of poziotinib in patients with recurrent and/or metastatic head and neck squamous cell carcinoma
por: Lee, Ji Hyun, et al.
Publicado: (2021)

Three SRA-Domain Methylcytosine-Binding Proteins Cooperate to Maintain Global CpG Methylation and Epigenetic Silencing in Arabidopsis
por: Woo, Hye Ryun, et al.
Publicado: (2008)

DNA Methylation Pattern as Important Epigenetic Criterion in Cancer
por: Ghavifekr Fakhr, Mehrdad, et al.
Publicado: (2013)

Distinct exhaustion features of T lymphocytes shape the tumor-immune microenvironment with therapeutic implication in patients with non-small-cell lung cancer
por: Kim, Chang Gon, et al.
Publicado: (2021)

Epigenetic mechanisms in virus-induced tumorigenesis
por: Poreba, Elzbieta, et al.
Publicado: (2011)

Knockdown of the Sodium-Dependent Phosphate Co-Transporter 2b (NPT2b) Suppresses Lung Tumorigenesis
por: Hong, Seong-Ho, et al.
Publicado: (2013)

Biphasic regulation of tumorigenesis by PTK7 expression level in esophageal squamous cell carcinoma
por: Shin, Won-Sik, et al.
Publicado: (2018)

Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative
por: Lim, Sun Min, et al.
Publicado: (2016)

Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis
por: Gu, Ruicai, et al.
Publicado: (2023)

Clinical implication of interstitial lung abnormality in elderly patients with early‐stage non‐small cell lung cancer
por: Cho, Seong Woo, et al.
Publicado: (2022)

EPHA3 Contributes to Epigenetic Suppression of PTEN in Radioresistant Head and Neck Cancer
por: Kim, Song-Hee, et al.
Publicado: (2021)

Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer
por: Shi, Yuan-Xiang, et al.
Publicado: (2017)

Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK‐rearranged lung cancer
por: Yun, Mi Ran, et al.
Publicado: (2019)

Correction: Knockdown of the Sodium-Dependent Phosphate Co-Transporter 2b (NPT2b) Suppresses Lung Tumorigenesis
por: Hong, Seong-Ho, et al.
Publicado: (2014)

Perilipin1 Expression as a Prognostic Factor in Patients with Squamous Cell Carcinoma of the Lung
por: Kim, Min Hye, et al.
Publicado: (2023)

Promoter methylation changes in ALOX12 and AIRE1: novel epigenetic markers for atherosclerosis
por: Kim, Jee Yeon, et al.
Publicado: (2020)

Transglutaminase 2 Expression Predicts Progression Free Survival in Non-Small Cell Lung Cancer Patients Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
por: Jeong, Jae-Heon, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_q36nnbuq08t6nqv6fk6ugaol1s