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Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury

The central nervous system (CNS) integrates sensory and motor information to acquire skilled movements, known as sensory-motor integration (SMI). The reciprocal interaction of the sensory and motor systems is a prerequisite for learning and performing skilled movement. Injury to various nodes of the...

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Autores principales: Asan, Ahmet S., McIntosh, James R., Carmel, Jason B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813971/
https://www.ncbi.nlm.nih.gov/pubmed/35126040
http://dx.doi.org/10.3389/fnins.2021.791824
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author Asan, Ahmet S.
McIntosh, James R.
Carmel, Jason B.
author_facet Asan, Ahmet S.
McIntosh, James R.
Carmel, Jason B.
author_sort Asan, Ahmet S.
collection PubMed
description The central nervous system (CNS) integrates sensory and motor information to acquire skilled movements, known as sensory-motor integration (SMI). The reciprocal interaction of the sensory and motor systems is a prerequisite for learning and performing skilled movement. Injury to various nodes of the sensorimotor network causes impairment in movement execution and learning. Stimulation methods have been developed to directly recruit the sensorimotor system and modulate neural networks to restore movement after CNS injury. Part 1 reviews the main processes and anatomical interactions responsible for SMI in health. Part 2 details the effects of injury on sites critical for SMI, including the spinal cord, cerebellum, and cerebral cortex. Finally, Part 3 reviews the application of activity-dependent plasticity in ways that specifically target integration of sensory and motor systems. Understanding of each of these components is needed to advance strategies targeting SMI to improve rehabilitation in humans after injury.
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spelling pubmed-88139712022-02-05 Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury Asan, Ahmet S. McIntosh, James R. Carmel, Jason B. Front Neurosci Neuroscience The central nervous system (CNS) integrates sensory and motor information to acquire skilled movements, known as sensory-motor integration (SMI). The reciprocal interaction of the sensory and motor systems is a prerequisite for learning and performing skilled movement. Injury to various nodes of the sensorimotor network causes impairment in movement execution and learning. Stimulation methods have been developed to directly recruit the sensorimotor system and modulate neural networks to restore movement after CNS injury. Part 1 reviews the main processes and anatomical interactions responsible for SMI in health. Part 2 details the effects of injury on sites critical for SMI, including the spinal cord, cerebellum, and cerebral cortex. Finally, Part 3 reviews the application of activity-dependent plasticity in ways that specifically target integration of sensory and motor systems. Understanding of each of these components is needed to advance strategies targeting SMI to improve rehabilitation in humans after injury. Frontiers Media S.A. 2022-01-21 /pmc/articles/PMC8813971/ /pubmed/35126040 http://dx.doi.org/10.3389/fnins.2021.791824 Text en Copyright © 2022 Asan, McIntosh and Carmel. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Asan, Ahmet S.
McIntosh, James R.
Carmel, Jason B.
Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title_full Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title_fullStr Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title_full_unstemmed Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title_short Targeting Sensory and Motor Integration for Recovery of Movement After CNS Injury
title_sort targeting sensory and motor integration for recovery of movement after cns injury
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813971/
https://www.ncbi.nlm.nih.gov/pubmed/35126040
http://dx.doi.org/10.3389/fnins.2021.791824
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