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Assortative mating biases marker-based heritability estimators

Many traits are subject to assortative mating, with recent molecular genetic findings confirming longstanding theoretical predictions that assortative mating induces long range dependence across causal variants. However, all marker-based heritability estimators implicitly assume mating is random. We...

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Detalles Bibliográficos
Autores principales:	Border, Richard, O’Rourke, Sean, de Candia, Teresa, Goddard, Michael E., Visscher, Peter M., Yengo, Loic, Jones, Matt, Keller, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814020/ https://www.ncbi.nlm.nih.gov/pubmed/35115518 http://dx.doi.org/10.1038/s41467-022-28294-9

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