Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

Increasingly, antibodies are being used to treat and prevent viral infections. In the context of HIV, efficacy is primarily attributed to dose-dependent neutralization potency and to a lesser extent Fc-mediated effector functions. It remains unclear whether augmenting effector functions of broadly n...

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Detalles Bibliográficos
Autores principales: Spencer, David A., Goldberg, Benjamin S., Pandey, Shilpi, Ordonez, Tracy, Dufloo, Jérémy, Barnette, Philip, Sutton, William F., Henderson, Heidi, Agnor, Rebecca, Gao, Lina, Bruel, Timothée, Schwartz, Olivier, Haigwood, Nancy L., Ackerman, Margaret E., Hessell, Ann J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814042/
https://www.ncbi.nlm.nih.gov/pubmed/35115533
http://dx.doi.org/10.1038/s41467-022-28250-7

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