Macrophage migration inhibitory factor is overproduced through EGR1 in TET2(low) resting monocytes

Somatic mutation in TET2 gene is one of the most common clonal genetic events detected in age-related clonal hematopoiesis as well as in chronic myelomonocytic leukemia (CMML). In addition to being a pre-malignant state, TET2 mutated clones are associated with an increased risk of death from cardiov...

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Detalles Bibliográficos
Autores principales: Pronier, Elodie, Imanci, Aygun, Selimoglu-Buet, Dorothée, Badaoui, Bouchra, Itzykson, Raphael, Roger, Thierry, Jego, Chloé, Naimo, Audrey, Francillette, Maëla, Breckler, Marie, Wagner-Ballon, Orianne, Figueroa, Maria E., Aglave, Marine, Gautheret, Daniel, Porteu, Françoise, Bernard, Olivier A., Vainchenker, William, Delhommeau, François, Solary, Eric, Droin, Nathalie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814058/
https://www.ncbi.nlm.nih.gov/pubmed/35115654
http://dx.doi.org/10.1038/s42003-022-03057-w

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