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E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis

Gasdermin D (GSDMD) participates in the activation of inflammasomes and pyroptosis. Meanwhile, ubiquitination strictly regulates inflammatory responses. However, how ubiquitination regulates Gasdermin D activity is not well understood. In this study, we show that pyroptosis triggered by Gasdermin D...

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Detalles Bibliográficos
Autores principales:	Shi, Yuhua, Yang, Yang, Xu, Weilv, Shi, Dongyun, Xu, Wei, Fu, Xinyu, Lv, Qian, Xia, Jie, Shi, Fushan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814081/ https://www.ncbi.nlm.nih.gov/pubmed/35115505 http://dx.doi.org/10.1038/s41419-022-04553-x

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