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Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice
The pruning of dendritic spines during development requires autophagy. This process is facilitated by long-term depression (LTD)-like mechanisms, which has led to speculation that LTD, a fundamental form of synaptic plasticity, also requires autophagy. Here, we show that the induction of LTD via act...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814153/ https://www.ncbi.nlm.nih.gov/pubmed/35115539 http://dx.doi.org/10.1038/s41467-022-28301-z |