Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice

The pruning of dendritic spines during development requires autophagy. This process is facilitated by long-term depression (LTD)-like mechanisms, which has led to speculation that LTD, a fundamental form of synaptic plasticity, also requires autophagy. Here, we show that the induction of LTD via act...

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Detalles Bibliográficos
Autores principales: Kallergi, Emmanouela, Daskalaki, Akrivi-Dimitra, Kolaxi, Angeliki, Camus, Come, Ioannou, Evangelia, Mercaldo, Valentina, Haberkant, Per, Stein, Frank, Sidiropoulou, Kyriaki, Dalezios, Yannis, Savitski, Mikhail M., Bagni, Claudia, Choquet, Daniel, Hosy, Eric, Nikoletopoulou, Vassiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814153/
https://www.ncbi.nlm.nih.gov/pubmed/35115539
http://dx.doi.org/10.1038/s41467-022-28301-z

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