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Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study

Vitamin D is necessary for musculoskeletal health, however, the supplementation of vitamin D above the sufficiency level does not bring additional bone mass density (BMD), unlike physical exercise which enhances the bone formatting process. Regular physical activity has been shown to upregulate VDR...

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Autores principales: Dzik, Katarzyna Patrycja, Grzywacz, Tomasz, Łuszczyk, Marcin, Kujach, Sylwester, Flis, Damian Józef, Kaczor, Jan Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814171/
https://www.ncbi.nlm.nih.gov/pubmed/35115578
http://dx.doi.org/10.1038/s41598-022-05783-x
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author Dzik, Katarzyna Patrycja
Grzywacz, Tomasz
Łuszczyk, Marcin
Kujach, Sylwester
Flis, Damian Józef
Kaczor, Jan Jacek
author_facet Dzik, Katarzyna Patrycja
Grzywacz, Tomasz
Łuszczyk, Marcin
Kujach, Sylwester
Flis, Damian Józef
Kaczor, Jan Jacek
author_sort Dzik, Katarzyna Patrycja
collection PubMed
description Vitamin D is necessary for musculoskeletal health, however, the supplementation of vitamin D above the sufficiency level does not bring additional bone mass density (BMD), unlike physical exercise which enhances the bone formatting process. Regular physical activity has been shown to upregulate VDR expression in muscles and to increase circulating vitamin D. Here we investigate whether a single bout of exercise might change 25(OH)D(3) blood concentration and how it affects metabolic response to exercise. Twenty-six boys, 13.8 years old (SD ± 0.7) soccer players, participated in the study. The participants performed one of two types of exercise: the first group performed the VO(2)max test until exhaustion, and the second performed three times the repeated 30 s Wingate Anaerobic Test (WAnT). Blood was collected before, 15 min and one hour after the exercise. The concentration of 25(OH)D(3), parathyroid hormone (PTH), interleukin-6 (IL-6), lactate, non-esterified fatty acids (NEFA) and glycerol were determined. 25(OH)D(3) concentration significantly increased after the exercise in all boys. The most prominent changes in 25(OH)D(3), observed after WAnT, were associated with the rise of PTH. The dimensions of response to the exercises observed through the changes in the concentration of 25(OH)D(3), PTH, NEFA and glycerol were associated with the significant increases of IL-6 level. A single bout of exercise may increase the serum’s 25(OH)D(3) concentration in young trained boys. The intensive interval exercise brings a more potent stimulus to vitamin D fluctuations in young organisms. Our results support the hypothesis that muscles may both store and release 25(OH)D(3).
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spelling pubmed-88141712022-02-07 Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study Dzik, Katarzyna Patrycja Grzywacz, Tomasz Łuszczyk, Marcin Kujach, Sylwester Flis, Damian Józef Kaczor, Jan Jacek Sci Rep Article Vitamin D is necessary for musculoskeletal health, however, the supplementation of vitamin D above the sufficiency level does not bring additional bone mass density (BMD), unlike physical exercise which enhances the bone formatting process. Regular physical activity has been shown to upregulate VDR expression in muscles and to increase circulating vitamin D. Here we investigate whether a single bout of exercise might change 25(OH)D(3) blood concentration and how it affects metabolic response to exercise. Twenty-six boys, 13.8 years old (SD ± 0.7) soccer players, participated in the study. The participants performed one of two types of exercise: the first group performed the VO(2)max test until exhaustion, and the second performed three times the repeated 30 s Wingate Anaerobic Test (WAnT). Blood was collected before, 15 min and one hour after the exercise. The concentration of 25(OH)D(3), parathyroid hormone (PTH), interleukin-6 (IL-6), lactate, non-esterified fatty acids (NEFA) and glycerol were determined. 25(OH)D(3) concentration significantly increased after the exercise in all boys. The most prominent changes in 25(OH)D(3), observed after WAnT, were associated with the rise of PTH. The dimensions of response to the exercises observed through the changes in the concentration of 25(OH)D(3), PTH, NEFA and glycerol were associated with the significant increases of IL-6 level. A single bout of exercise may increase the serum’s 25(OH)D(3) concentration in young trained boys. The intensive interval exercise brings a more potent stimulus to vitamin D fluctuations in young organisms. Our results support the hypothesis that muscles may both store and release 25(OH)D(3). Nature Publishing Group UK 2022-02-03 /pmc/articles/PMC8814171/ /pubmed/35115578 http://dx.doi.org/10.1038/s41598-022-05783-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Dzik, Katarzyna Patrycja
Grzywacz, Tomasz
Łuszczyk, Marcin
Kujach, Sylwester
Flis, Damian Józef
Kaczor, Jan Jacek
Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title_full Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title_fullStr Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title_full_unstemmed Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title_short Single bout of exercise triggers the increase of vitamin D blood concentration in adolescent trained boys: a pilot study
title_sort single bout of exercise triggers the increase of vitamin d blood concentration in adolescent trained boys: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814171/
https://www.ncbi.nlm.nih.gov/pubmed/35115578
http://dx.doi.org/10.1038/s41598-022-05783-x
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