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Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network

Automatic segmentation of infected lesions from computed tomography (CT) of COVID-19 patients is crucial for accurate diagnosis and follow-up assessment. The remaining challenges are the obvious scale difference between different types of COVID-19 lesions and the similarity between the lesions and n...

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Autores principales: Zhang, Jianxiong, Ding, Xuefeng, Hu, Dasha, Jiang, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814191/
https://www.ncbi.nlm.nih.gov/pubmed/35115573
http://dx.doi.org/10.1038/s41598-022-05527-x
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author Zhang, Jianxiong
Ding, Xuefeng
Hu, Dasha
Jiang, Yuming
author_facet Zhang, Jianxiong
Ding, Xuefeng
Hu, Dasha
Jiang, Yuming
author_sort Zhang, Jianxiong
collection PubMed
description Automatic segmentation of infected lesions from computed tomography (CT) of COVID-19 patients is crucial for accurate diagnosis and follow-up assessment. The remaining challenges are the obvious scale difference between different types of COVID-19 lesions and the similarity between the lesions and normal tissues. This work aims to segment lesions of different scales and lesion boundaries correctly by utilizing multiscale and multilevel features. A novel multiscale dilated convolutional network (MSDC-Net) is proposed against the scale difference of lesions and the low contrast between lesions and normal tissues in CT images. In our MSDC-Net, we propose a multiscale feature capture block (MSFCB) to effectively capture multiscale features for better segmentation of lesions at different scales. Furthermore, a multilevel feature aggregate (MLFA) module is proposed to reduce the information loss in the downsampling process. Experiments on the publicly available COVID-19 CT Segmentation dataset demonstrate that the proposed MSDC-Net is superior to other existing methods in segmenting lesion boundaries and large, medium, and small lesions, and achieves the best results in Dice similarity coefficient, sensitivity and mean intersection-over-union (mIoU) scores of 82.4%, 81.1% and 78.2%, respectively. Compared with other methods, the proposed model has an average improvement of 10.6% and 11.8% on Dice and mIoU. Compared with the existing methods, our network achieves more accurate segmentation of lesions at various scales and lesion boundaries, which will facilitate further clinical analysis. In the future, we consider integrating the automatic detection and segmentation of COVID-19, and conduct research on the automatic diagnosis system of COVID-19.
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spelling pubmed-88141912022-02-07 Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network Zhang, Jianxiong Ding, Xuefeng Hu, Dasha Jiang, Yuming Sci Rep Article Automatic segmentation of infected lesions from computed tomography (CT) of COVID-19 patients is crucial for accurate diagnosis and follow-up assessment. The remaining challenges are the obvious scale difference between different types of COVID-19 lesions and the similarity between the lesions and normal tissues. This work aims to segment lesions of different scales and lesion boundaries correctly by utilizing multiscale and multilevel features. A novel multiscale dilated convolutional network (MSDC-Net) is proposed against the scale difference of lesions and the low contrast between lesions and normal tissues in CT images. In our MSDC-Net, we propose a multiscale feature capture block (MSFCB) to effectively capture multiscale features for better segmentation of lesions at different scales. Furthermore, a multilevel feature aggregate (MLFA) module is proposed to reduce the information loss in the downsampling process. Experiments on the publicly available COVID-19 CT Segmentation dataset demonstrate that the proposed MSDC-Net is superior to other existing methods in segmenting lesion boundaries and large, medium, and small lesions, and achieves the best results in Dice similarity coefficient, sensitivity and mean intersection-over-union (mIoU) scores of 82.4%, 81.1% and 78.2%, respectively. Compared with other methods, the proposed model has an average improvement of 10.6% and 11.8% on Dice and mIoU. Compared with the existing methods, our network achieves more accurate segmentation of lesions at various scales and lesion boundaries, which will facilitate further clinical analysis. In the future, we consider integrating the automatic detection and segmentation of COVID-19, and conduct research on the automatic diagnosis system of COVID-19. Nature Publishing Group UK 2022-02-03 /pmc/articles/PMC8814191/ /pubmed/35115573 http://dx.doi.org/10.1038/s41598-022-05527-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhang, Jianxiong
Ding, Xuefeng
Hu, Dasha
Jiang, Yuming
Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title_full Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title_fullStr Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title_full_unstemmed Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title_short Semantic segmentation of COVID-19 lesions with a multiscale dilated convolutional network
title_sort semantic segmentation of covid-19 lesions with a multiscale dilated convolutional network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814191/
https://www.ncbi.nlm.nih.gov/pubmed/35115573
http://dx.doi.org/10.1038/s41598-022-05527-x
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