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The anti-osteosarcoma cell activity by the sphingosine kinase 1 inhibitor SKI-V

Sphingosine kinase 1 (SphK1) expression and activity are elevated in human osteosarcoma (OS) and is a promising target of therapy. SKI-V is a non-competitive and highly-efficient non-lipid SphK1 inhibitor. The potential anti-OS cell activity by the SphK1 inhibitor was studied here. In primary OS cel...

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Detalles Bibliográficos
Autores principales:	Sun, Xu, Shan, Hua-jian, Yin, Gang, Zhang, Xiang-yang, Huang, Yu-min, Li, Hai-jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814198/ https://www.ncbi.nlm.nih.gov/pubmed/35115496 http://dx.doi.org/10.1038/s41420-022-00838-4

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