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Rivastigmine Regulates the HIF-1α/VEGF Signaling Pathway to Induce Angiogenesis and Improves the Survival of Random Flaps in Rats

Random skin flaps are frequently used to repair skin damage. However, the ischemic and hypoxic necrosis limits their wider application. Rivastigmine, a carbamate cholinesterase inhibitor (ChEI), has also been shown to reduce ischemia–reperfusion injury (IRI) and inflammation. This study was performe...

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Detalles Bibliográficos
Autores principales: Liu, Yingying, Li, Wenjie, Ma, Xinyi, He, Jibing, Lin, Yi, Lin, Dingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814337/
https://www.ncbi.nlm.nih.gov/pubmed/35126151
http://dx.doi.org/10.3389/fphar.2021.818907