1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents

A wide range of biological activities is exhibited by 1,3,4-thiadiazole moiety such as antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral, antihypertensive, and antimicrobial. To date, drugs such as butazolamide, and acetazolamide. Several modifications have been done in the 1,3,...

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Detalles Bibliográficos
Autores principales: Anthwal, Tulika, Nain, Sumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814426/
https://www.ncbi.nlm.nih.gov/pubmed/35127639
http://dx.doi.org/10.3389/fchem.2021.671212
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author Anthwal, Tulika
Nain, Sumitra
author_facet Anthwal, Tulika
Nain, Sumitra
author_sort Anthwal, Tulika
collection PubMed
description A wide range of biological activities is exhibited by 1,3,4-thiadiazole moiety such as antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral, antihypertensive, and antimicrobial. To date, drugs such as butazolamide, and acetazolamide. Several modifications have been done in the 1,3,4-thiadiazole moiety which showed good potency as anticonvulsant agents which are highly effective and have less toxicity. After in-depth literature survey in this review, we have compiled various derivatives of 1,3,4-thiadiazole scaffold as anticonvulsant agents.
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spelling pubmed-88144262022-02-05 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents Anthwal, Tulika Nain, Sumitra Front Chem Chemistry A wide range of biological activities is exhibited by 1,3,4-thiadiazole moiety such as antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral, antihypertensive, and antimicrobial. To date, drugs such as butazolamide, and acetazolamide. Several modifications have been done in the 1,3,4-thiadiazole moiety which showed good potency as anticonvulsant agents which are highly effective and have less toxicity. After in-depth literature survey in this review, we have compiled various derivatives of 1,3,4-thiadiazole scaffold as anticonvulsant agents. Frontiers Media S.A. 2022-01-21 /pmc/articles/PMC8814426/ /pubmed/35127639 http://dx.doi.org/10.3389/fchem.2021.671212 Text en Copyright © 2022 Anthwal and Nain. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Anthwal, Tulika
Nain, Sumitra
1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title_full 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title_fullStr 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title_full_unstemmed 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title_short 1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents
title_sort 1,3,4-thiadiazole scaffold: as anti-epileptic agents
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814426/
https://www.ncbi.nlm.nih.gov/pubmed/35127639
http://dx.doi.org/10.3389/fchem.2021.671212
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