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RNA-Cholesterol Nanoparticles Function as Potent Immune Activators via TLR7 and TLR8

The innate immune system senses viral and bacterial ribonucleic acid (RNA) via pattern recognition receptors (PRR) leading to subsequent activation of the immune system. One group of RNA sensors is formed by endosomal/lysosomal Toll-like receptors (TLR) such as TLR7 and TLR8. During viral or bacteri...

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Detalles Bibliográficos
Autores principales:	Obermann, Hannah-Lena, Lederbogen, Ines I., Steele, Jenny, Dorna, Jens, Sander, Leif Erik, Engelhardt, Konrad, Bakowsky, Udo, Kaufmann, Andreas, Bauer, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814444/ https://www.ncbi.nlm.nih.gov/pubmed/35126343 http://dx.doi.org/10.3389/fimmu.2021.658895

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