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Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension

AIMS: The incidence of atrioventricular nodal reentrant tachycardia (AVNRT) is higher in pulmonary arterial hypertension (PAH) patients than in the general population. AVNRT is reportedly associated with a larger coronary sinus (CS) ostium (CSo). However, the correlation between AVNRT and CSo size i...

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Autores principales: Ding, Lei, Weng, Sixian, Zhai, Zhengqin, Zhou, Bin, Qi, Yingjie, Yu, Fengyuan, Zhang, Hongda, Zhang, Shu, Tang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814530/
https://www.ncbi.nlm.nih.gov/pubmed/35126179
http://dx.doi.org/10.3389/fphys.2021.790077
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author Ding, Lei
Weng, Sixian
Zhai, Zhengqin
Zhou, Bin
Qi, Yingjie
Yu, Fengyuan
Zhang, Hongda
Zhang, Shu
Tang, Min
author_facet Ding, Lei
Weng, Sixian
Zhai, Zhengqin
Zhou, Bin
Qi, Yingjie
Yu, Fengyuan
Zhang, Hongda
Zhang, Shu
Tang, Min
author_sort Ding, Lei
collection PubMed
description AIMS: The incidence of atrioventricular nodal reentrant tachycardia (AVNRT) is higher in pulmonary arterial hypertension (PAH) patients than in the general population. AVNRT is reportedly associated with a larger coronary sinus (CS) ostium (CSo). However, the correlation between AVNRT and CSo size in PAH patients is poorly investigated. We aimed to investigate the impact of CSo size on AVNRT and identify its risk factors in PAH. METHODS AND RESULTS: Of 102 PAH patients with catheter ablation of supraventricular tachycardia (SVT), twelve with a confirmed AVNRT diagnosis who underwent computed tomographic angiography were retrospectively enrolled as the study group. The control group (PAH without SVT, n = 24) was matched for sex and BMI at a 2:1 ratio. All baseline and imaging data were collected. Mean pulmonary artery pressure was not significantly different between the two groups (65.3 ± 16.8 vs. 64.5 ± 17.6 mmHg, P = 0.328). PAH patients with AVNRT were older (45.9 ± 14.8 vs. 32.1 ± 7.6 years, P = 0.025), had a larger right atrial volume (224.4 ± 129.6 vs. 165.3 ± 71.7 cm(3), P = 0.044), larger CSo in the left anterior oblique (LAO) plane (18.6 ± 3.3 vs. 14.8 ± 4.0 mm, P = 0.011), and larger CSo surface area (2.08 ± 1.35 vs. 1.45 ± 0.73 cm(2), P = 0.039) and were more likely to have a windsock-shape CS (75% vs. 16.7%, P = 0.001) than those without AVNRT. A linear correlation was shown between CSo diameter in the LAO-plane and the atrial fractionation of the ablation target for AVNRT (R(2) = 0.622, P = 0.012). CONCLUSION: Anatomical dilation of the CSo is a risk factor for AVNRT development in patients with PAH.
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spelling pubmed-88145302022-02-05 Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension Ding, Lei Weng, Sixian Zhai, Zhengqin Zhou, Bin Qi, Yingjie Yu, Fengyuan Zhang, Hongda Zhang, Shu Tang, Min Front Physiol Physiology AIMS: The incidence of atrioventricular nodal reentrant tachycardia (AVNRT) is higher in pulmonary arterial hypertension (PAH) patients than in the general population. AVNRT is reportedly associated with a larger coronary sinus (CS) ostium (CSo). However, the correlation between AVNRT and CSo size in PAH patients is poorly investigated. We aimed to investigate the impact of CSo size on AVNRT and identify its risk factors in PAH. METHODS AND RESULTS: Of 102 PAH patients with catheter ablation of supraventricular tachycardia (SVT), twelve with a confirmed AVNRT diagnosis who underwent computed tomographic angiography were retrospectively enrolled as the study group. The control group (PAH without SVT, n = 24) was matched for sex and BMI at a 2:1 ratio. All baseline and imaging data were collected. Mean pulmonary artery pressure was not significantly different between the two groups (65.3 ± 16.8 vs. 64.5 ± 17.6 mmHg, P = 0.328). PAH patients with AVNRT were older (45.9 ± 14.8 vs. 32.1 ± 7.6 years, P = 0.025), had a larger right atrial volume (224.4 ± 129.6 vs. 165.3 ± 71.7 cm(3), P = 0.044), larger CSo in the left anterior oblique (LAO) plane (18.6 ± 3.3 vs. 14.8 ± 4.0 mm, P = 0.011), and larger CSo surface area (2.08 ± 1.35 vs. 1.45 ± 0.73 cm(2), P = 0.039) and were more likely to have a windsock-shape CS (75% vs. 16.7%, P = 0.001) than those without AVNRT. A linear correlation was shown between CSo diameter in the LAO-plane and the atrial fractionation of the ablation target for AVNRT (R(2) = 0.622, P = 0.012). CONCLUSION: Anatomical dilation of the CSo is a risk factor for AVNRT development in patients with PAH. Frontiers Media S.A. 2022-01-21 /pmc/articles/PMC8814530/ /pubmed/35126179 http://dx.doi.org/10.3389/fphys.2021.790077 Text en Copyright © 2022 Ding, Weng, Zhai, Zhou, Qi, Yu, Zhang, Zhang and Tang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Ding, Lei
Weng, Sixian
Zhai, Zhengqin
Zhou, Bin
Qi, Yingjie
Yu, Fengyuan
Zhang, Hongda
Zhang, Shu
Tang, Min
Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title_full Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title_fullStr Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title_full_unstemmed Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title_short Association Between the Coronary Sinus Ostial Size and Atrioventricular Nodal Reentrant Tachycardia in Patients With Pulmonary Arterial Hypertension
title_sort association between the coronary sinus ostial size and atrioventricular nodal reentrant tachycardia in patients with pulmonary arterial hypertension
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814530/
https://www.ncbi.nlm.nih.gov/pubmed/35126179
http://dx.doi.org/10.3389/fphys.2021.790077
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