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Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults

BACKGROUND: Frailty and cognitive impairment are significant problems faced by older adults, which have a significant impact on their activities of daily living, social activities, and quality of life. DESIGN: Cross-sectional study. METHODS: A total of 252 older adults in two communities in Yangzhou...

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Autores principales: Xue, Huiping, Huang, Chunxia, Zhu, Qin, Zhou, Shuixin, Ji, Yunlan, Ding, Xiaohui, Zhang, Dandan, Gu, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814599/
https://www.ncbi.nlm.nih.gov/pubmed/35126090
http://dx.doi.org/10.3389/fnagi.2021.790251
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author Xue, Huiping
Huang, Chunxia
Zhu, Qin
Zhou, Shuixin
Ji, Yunlan
Ding, Xiaohui
Zhang, Dandan
Gu, Dongmei
author_facet Xue, Huiping
Huang, Chunxia
Zhu, Qin
Zhou, Shuixin
Ji, Yunlan
Ding, Xiaohui
Zhang, Dandan
Gu, Dongmei
author_sort Xue, Huiping
collection PubMed
description BACKGROUND: Frailty and cognitive impairment are significant problems faced by older adults, which have a significant impact on their activities of daily living, social activities, and quality of life. DESIGN: Cross-sectional study. METHODS: A total of 252 older adults in two communities in Yangzhou were randomly selected. The cognitive function of the elderly was assessed using the Memory and Executive Screening (MES). The frailty phenotype was used to evaluate the frail situation of older adults. The activity of daily living (ADL), functional activities questionnaire (FAQ), and European quality of 5-dimensions (EQ-5D) were used to evaluate health outcomes in the elderly. SEM was used to explore the direct and indirect relationship among cognitive function, frailty and health outcomes. RESULTS: There was a significant direct correlation between cognitive function and frailty; the direct effect was −0.521. The influence path of cognitive function on health outcomes included direct and indirect effects; the total effect was −0.759. The effect of frailty on health outcomes included direct and indirect effects; the total effect was 0.440. CONCLUSION: According to SEM, cognitive function interacts with frailty and may reduce the quality of life, the ADL, and social activities among older adults directly and indirectly, so future assessments of older adults should consider both cognitive function and frailty, so as to further improve the health outcome of the elderly. When formulating relevant intervention measures in the future, we need to consider that it cannot only improve the cognitive function, but also improve the frail situation, so as to jointly improve the health outcomes of older adults.
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spelling pubmed-88145992022-02-05 Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults Xue, Huiping Huang, Chunxia Zhu, Qin Zhou, Shuixin Ji, Yunlan Ding, Xiaohui Zhang, Dandan Gu, Dongmei Front Aging Neurosci Aging Neuroscience BACKGROUND: Frailty and cognitive impairment are significant problems faced by older adults, which have a significant impact on their activities of daily living, social activities, and quality of life. DESIGN: Cross-sectional study. METHODS: A total of 252 older adults in two communities in Yangzhou were randomly selected. The cognitive function of the elderly was assessed using the Memory and Executive Screening (MES). The frailty phenotype was used to evaluate the frail situation of older adults. The activity of daily living (ADL), functional activities questionnaire (FAQ), and European quality of 5-dimensions (EQ-5D) were used to evaluate health outcomes in the elderly. SEM was used to explore the direct and indirect relationship among cognitive function, frailty and health outcomes. RESULTS: There was a significant direct correlation between cognitive function and frailty; the direct effect was −0.521. The influence path of cognitive function on health outcomes included direct and indirect effects; the total effect was −0.759. The effect of frailty on health outcomes included direct and indirect effects; the total effect was 0.440. CONCLUSION: According to SEM, cognitive function interacts with frailty and may reduce the quality of life, the ADL, and social activities among older adults directly and indirectly, so future assessments of older adults should consider both cognitive function and frailty, so as to further improve the health outcome of the elderly. When formulating relevant intervention measures in the future, we need to consider that it cannot only improve the cognitive function, but also improve the frail situation, so as to jointly improve the health outcomes of older adults. Frontiers Media S.A. 2022-01-21 /pmc/articles/PMC8814599/ /pubmed/35126090 http://dx.doi.org/10.3389/fnagi.2021.790251 Text en Copyright © 2022 Xue, Huang, Zhu, Zhou, Ji, Ding, Zhang and Gu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging Neuroscience
Xue, Huiping
Huang, Chunxia
Zhu, Qin
Zhou, Shuixin
Ji, Yunlan
Ding, Xiaohui
Zhang, Dandan
Gu, Dongmei
Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title_full Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title_fullStr Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title_full_unstemmed Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title_short Relationships Among Cognitive Function, Frailty, and Health Outcome in Community-Dwelling Older Adults
title_sort relationships among cognitive function, frailty, and health outcome in community-dwelling older adults
topic Aging Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814599/
https://www.ncbi.nlm.nih.gov/pubmed/35126090
http://dx.doi.org/10.3389/fnagi.2021.790251
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