Neutralizing Anti-IL-17A Antibody Demonstrates Preclinical Activity Enhanced by Vinblastine in Langerhans Cell Histiocytosis

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasm characterised by the accumulation into granulomas of apoptosis-resistant pathological dendritic cells (LCH-DCs). LCH outcome ranges from self-resolving to fatal. Having previously shown that, (i) monocyte-derived DCs (Mo-DCs) fr...

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Detalles Bibliográficos
Autores principales: Åkefeldt, Selma Olsson, Ismail, Mohamad Bachar, Belot, Alexandre, Salvatore, Giulia, Bissay, Nathalie, Gavhed, Désirée, Aricò, Maurizio, Henter, Jan-Inge, Valentin, Hélène, Delprat, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814633/
https://www.ncbi.nlm.nih.gov/pubmed/35127485
http://dx.doi.org/10.3389/fonc.2021.780191

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