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Inhibition of high-fat diet–induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms
Obesity is a risk factor for insulin resistance, type 2 diabetes, and cardiovascular diseases. Reticulon-4 (Nogo) is an endoplasmic reticulum–resident protein with unclear functions in obesity. Herein, we investigated the effect of Nogo on obesity and associated metabolic disorders. Human serum samp...
Autores principales: | Wang, Xiaolin, Yang, Yanfang, Zhao, Dan, Zhang, Shuang, Chen, Yi, Chen, Yuanli, Feng, Ke, Li, Xiaoju, Han, Jihong, Iwakiri, Yasuko, Duan, Yajun, Yang, Xiaoxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814669/ https://www.ncbi.nlm.nih.gov/pubmed/34998825 http://dx.doi.org/10.1016/j.jbc.2022.101561 |
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