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miR-154-5p Affects the TGFβ1/Smad3 Pathway on the Fibrosis of Diabetic Kidney Disease via Binding E3 Ubiquitin Ligase Smurf1

AIM: The study is aimed at verifying miR-154-5p and Smurf1 combination in glomerular mesangial cells regulating TGFβ1/Smad3 pathway-related protein ubiquitination in the model of diabetic rats renal tissues, primary mesangial cells, and cell lines. METHODS: The diabetic SD rat model and high-glucose...

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Detalles Bibliográficos
Autores principales: Bian, Che, Luan, Zhilin, Zhang, Haibo, Zhang, Ruijing, Gao, Jing, Wang, Yuxia, Li, Jia, Ren, Huiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814716/
https://www.ncbi.nlm.nih.gov/pubmed/35126820
http://dx.doi.org/10.1155/2022/7502632

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