Cargando…

Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?

BACKGROUND: This was a randomized controlled clinical trial that aimed to evaluate the anesthetic efficacy of 2% lidocaine combined with different concentrations of epinephrine (plain, 1:200,000 and 1:80,000) during endodontic treatment of maxillary molars with symptomatic irreversible pulpitis. MET...

Descripción completa

Detalles Bibliográficos
Autores principales: Singla, Mamta, Gugnani, Megha, Grewal, Mandeep S, Kumar, Umesh, Aggarwal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dental Society of Anesthsiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814729/
https://www.ncbi.nlm.nih.gov/pubmed/35169619
http://dx.doi.org/10.17245/jdapm.2022.22.1.39
_version_ 1784645127085490176
author Singla, Mamta
Gugnani, Megha
Grewal, Mandeep S
Kumar, Umesh
Aggarwal, Vivek
author_facet Singla, Mamta
Gugnani, Megha
Grewal, Mandeep S
Kumar, Umesh
Aggarwal, Vivek
author_sort Singla, Mamta
collection PubMed
description BACKGROUND: This was a randomized controlled clinical trial that aimed to evaluate the anesthetic efficacy of 2% lidocaine combined with different concentrations of epinephrine (plain, 1:200,000 and 1:80,000) during endodontic treatment of maxillary molars with symptomatic irreversible pulpitis. METHODS: The trial included 144 adult patients who were randomly allocated to three treatment groups. All patients received buccal-plus-palatal infiltration. After 10 min, pulp sensibility testing was performed using an electric pulp test (EPT). If a tooth responded positively, anesthesia was considered to have failed. In the case of a negative EPT response, endodontic access was initiated under rubber dam isolation. The success of anesthesia was defined as having a pain score less than 55 on the Heft Parker visual analog scale (HP VAS), which was categorized as ‘no pain’ or ‘faint/weak/mild’ pain on the HP VAS. Baseline pre-injection and post-injection maximum heart rates were recorded. The Pearson chi-square test was used to analyze the anesthetic success rates at 5% significance. RESULTS: Plain 2% lidocaine and 2% lidocaine with 1:200,000 epinephrine and 1:80,000 epinephrine had anesthetic success rates of 18.75%, 72.9%, and 82.3%, respectively. Statistical analysis indicated significant differences between the groups (P < 0.001, χ(2) = 47.5, df = 2). The maximum heart rate increase was seen with 2% lidocaine solution with epinephrine. CONCLUSION: Adding epinephrine to 2% lidocaine significantly improves its anesthetic success rates during the root canal treatment of maxillary molars with symptomatic irreversible pulpitis.
format Online
Article
Text
id pubmed-8814729
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Korean Dental Society of Anesthsiology
record_format MEDLINE/PubMed
spelling pubmed-88147292022-02-14 Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis? Singla, Mamta Gugnani, Megha Grewal, Mandeep S Kumar, Umesh Aggarwal, Vivek J Dent Anesth Pain Med Original Article BACKGROUND: This was a randomized controlled clinical trial that aimed to evaluate the anesthetic efficacy of 2% lidocaine combined with different concentrations of epinephrine (plain, 1:200,000 and 1:80,000) during endodontic treatment of maxillary molars with symptomatic irreversible pulpitis. METHODS: The trial included 144 adult patients who were randomly allocated to three treatment groups. All patients received buccal-plus-palatal infiltration. After 10 min, pulp sensibility testing was performed using an electric pulp test (EPT). If a tooth responded positively, anesthesia was considered to have failed. In the case of a negative EPT response, endodontic access was initiated under rubber dam isolation. The success of anesthesia was defined as having a pain score less than 55 on the Heft Parker visual analog scale (HP VAS), which was categorized as ‘no pain’ or ‘faint/weak/mild’ pain on the HP VAS. Baseline pre-injection and post-injection maximum heart rates were recorded. The Pearson chi-square test was used to analyze the anesthetic success rates at 5% significance. RESULTS: Plain 2% lidocaine and 2% lidocaine with 1:200,000 epinephrine and 1:80,000 epinephrine had anesthetic success rates of 18.75%, 72.9%, and 82.3%, respectively. Statistical analysis indicated significant differences between the groups (P < 0.001, χ(2) = 47.5, df = 2). The maximum heart rate increase was seen with 2% lidocaine solution with epinephrine. CONCLUSION: Adding epinephrine to 2% lidocaine significantly improves its anesthetic success rates during the root canal treatment of maxillary molars with symptomatic irreversible pulpitis. The Korean Dental Society of Anesthsiology 2022-02 2022-01-24 /pmc/articles/PMC8814729/ /pubmed/35169619 http://dx.doi.org/10.17245/jdapm.2022.22.1.39 Text en Copyright © 2022 Journal of Dental Anesthesia and Pain Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Singla, Mamta
Gugnani, Megha
Grewal, Mandeep S
Kumar, Umesh
Aggarwal, Vivek
Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title_full Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title_fullStr Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title_full_unstemmed Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title_short Does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
title_sort does the presence and amount of epinephrine in 2% lidocaine affect its anesthetic efficacy in the management of symptomatic maxillary molars with irreversible pulpitis?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814729/
https://www.ncbi.nlm.nih.gov/pubmed/35169619
http://dx.doi.org/10.17245/jdapm.2022.22.1.39
work_keys_str_mv AT singlamamta doesthepresenceandamountofepinephrinein2lidocaineaffectitsanestheticefficacyinthemanagementofsymptomaticmaxillarymolarswithirreversiblepulpitis
AT gugnanimegha doesthepresenceandamountofepinephrinein2lidocaineaffectitsanestheticefficacyinthemanagementofsymptomaticmaxillarymolarswithirreversiblepulpitis
AT grewalmandeeps doesthepresenceandamountofepinephrinein2lidocaineaffectitsanestheticefficacyinthemanagementofsymptomaticmaxillarymolarswithirreversiblepulpitis
AT kumarumesh doesthepresenceandamountofepinephrinein2lidocaineaffectitsanestheticefficacyinthemanagementofsymptomaticmaxillarymolarswithirreversiblepulpitis
AT aggarwalvivek doesthepresenceandamountofepinephrinein2lidocaineaffectitsanestheticefficacyinthemanagementofsymptomaticmaxillarymolarswithirreversiblepulpitis