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Mechanical phenotyping reveals unique biomechanical responses in retinoic acid-resistant acute promyelocytic leukemia

All-trans retinoic acid (ATRA) is an essential therapy in the treatment of acute promyelocytic leukemia (APL), but nearly 20% of patients with APL are resistant to ATRA. As there are no biomarkers for ATRA resistance that yet exist, we investigated whether cell mechanics could be associated with thi...

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Detalles Bibliográficos
Autores principales:	Li, Brian, Maslan, Annie, Kitayama, Sean E., Pierce, Corinne, Streets, Aaron M., Sohn, Lydia L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814755/ https://www.ncbi.nlm.nih.gov/pubmed/35141508 http://dx.doi.org/10.1016/j.isci.2022.103772

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