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Global conserved RBD fraction of SARS-CoV-2 S-protein with T500S mutation in silico significantly blocks ACE2 and rejects viral spike

BACKGROUND: SARS-CoV-2 developed global-pandemic with millions of infections/deaths. As it is urgently necessary it is assumed that some blockers/inhibitors of ACE2 could be helpful to resist the binding of viral-spike Receptor-Binding-Domain (RBD). METHODS: Here, conserved RBD from 186-countries we...

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Detalles Bibliográficos
Autores principales: Banerjee, Amrita, Kanwar, Mehak, Santra, Dipannita, Maiti, Smarajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814807/
https://www.ncbi.nlm.nih.gov/pubmed/35136839
http://dx.doi.org/10.1186/s41231-022-00109-5

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