Alx1 Deficient Mice Recapitulate Craniofacial Phenotype and Reveal Developmental Basis of ALX1-Related Frontonasal Dysplasia

Loss of ALX1 function causes the frontonasal dysplasia syndrome FND3, characterized by severe facial clefting and microphthalmia. Whereas the laboratory mouse has been the preeminent animal model for studying developmental mechanisms of human craniofacial birth defects, the roles of ALX1 in mouse fr...

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Detalles Bibliográficos
Autores principales: Iyyanar, Paul P. R., Wu, Zhaoming, Lan, Yu, Hu, Yueh-Chiang, Jiang, Rulang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815032/
https://www.ncbi.nlm.nih.gov/pubmed/35127681
http://dx.doi.org/10.3389/fcell.2022.777887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815032/
https://www.ncbi.nlm.nih.gov/pubmed/35127681
http://dx.doi.org/10.3389/fcell.2022.777887

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