Specific Silencing of Microglial Gene Expression in the Rat Brain by Nanoparticle-Based Small Interfering RNA Delivery

[Image: see text] Microglia are the major innate immune cells in the brain and are essential for maintaining homeostasis in a neuronal microenvironment. Currently, a genetic tool to modify microglial gene expression in specific brain regions is not available. In this report, we introduce a tailor-de...

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Detalles Bibliográficos
Autores principales: Guo, Shanshan, Cázarez-Márquez, Fernando, Jiao, Han, Foppen, Ewout, Korpel, Nikita L., Grootemaat, Anita E., Liv, Nalan, Gao, Yuanqing, van der Wel, Nicole, Zhou, Bing, Nie, Guangjun, Yi, Chun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815040/
https://www.ncbi.nlm.nih.gov/pubmed/35041392
http://dx.doi.org/10.1021/acsami.1c22434

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