Comparison of mixed model based approaches for correcting for population substructure with application to extreme phenotype sampling

BACKGROUND: Mixed models are used to correct for confounding due to population stratification and hidden relatedness in genome-wide association studies. This class of models includes linear mixed models and generalized linear mixed models. Existing mixed model approaches to correct for population su...

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Detalles Bibliográficos
Autores principales: Onifade, Maryam, Roy-Gagnon, Marie-Hélène, Parent, Marie-Élise, Burkett, Kelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815214/
https://www.ncbi.nlm.nih.gov/pubmed/35120458
http://dx.doi.org/10.1186/s12864-022-08297-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815214/
https://www.ncbi.nlm.nih.gov/pubmed/35120458
http://dx.doi.org/10.1186/s12864-022-08297-y

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