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Comparison of mixed model based approaches for correcting for population substructure with application to extreme phenotype sampling
BACKGROUND: Mixed models are used to correct for confounding due to population stratification and hidden relatedness in genome-wide association studies. This class of models includes linear mixed models and generalized linear mixed models. Existing mixed model approaches to correct for population su...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815214/ https://www.ncbi.nlm.nih.gov/pubmed/35120458 http://dx.doi.org/10.1186/s12864-022-08297-y |