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Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management

Right ventricular (RV) metastasis from an upper tract urothelial carcinoma without inferior vena cava or right atrial involvement is an extremely rare event which highlights the heterogeneity of this disease process. We report a case of a 43-year-old man presenting for long-standing hematuria and le...

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Autores principales: Helman, Talia A., Imam, Ahmad Saeed, Espino-Grosso, Pedro, Patel, Trushar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815341/
https://www.ncbi.nlm.nih.gov/pubmed/35197710
http://dx.doi.org/10.4103/UA.UA_157_20
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author Helman, Talia A.
Imam, Ahmad Saeed
Espino-Grosso, Pedro
Patel, Trushar
author_facet Helman, Talia A.
Imam, Ahmad Saeed
Espino-Grosso, Pedro
Patel, Trushar
author_sort Helman, Talia A.
collection PubMed
description Right ventricular (RV) metastasis from an upper tract urothelial carcinoma without inferior vena cava or right atrial involvement is an extremely rare event which highlights the heterogeneity of this disease process. We report a case of a 43-year-old man presenting for long-standing hematuria and left flank pain. Computed tomography revealed a left renal mass with para-aortic lymphadenopathy, in addition to a potential mass in the RV. The mass involving the RV was confirmed on subsequent cardiac evaluation with magnetic resonance imaging (MRI) and echocardiography. After discussion in a multidisciplinary tumor board, the patient underwent a left nephrectomy, regional lymphadenectomy, and excision of metastatic RV tumor with bovine patch reconstruction. Final pathology reported invasive urothelial carcinoma in the left kidney with involvement of regional para-aortic lymph nodes and metastatic tumor in the RV (T4N3M1, AJCC 8(th) edition). The patient did well postoperatively and completed adjuvant Cisplatin-Gemcitabine systemic chemotherapy. This is an important addition to the literature as it highlights the aggressive and heterogeneous nature of urothelial carcinoma and the utility of cardiac MRI in surgical planning.
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spelling pubmed-88153412022-02-22 Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management Helman, Talia A. Imam, Ahmad Saeed Espino-Grosso, Pedro Patel, Trushar Urol Ann Case Report Right ventricular (RV) metastasis from an upper tract urothelial carcinoma without inferior vena cava or right atrial involvement is an extremely rare event which highlights the heterogeneity of this disease process. We report a case of a 43-year-old man presenting for long-standing hematuria and left flank pain. Computed tomography revealed a left renal mass with para-aortic lymphadenopathy, in addition to a potential mass in the RV. The mass involving the RV was confirmed on subsequent cardiac evaluation with magnetic resonance imaging (MRI) and echocardiography. After discussion in a multidisciplinary tumor board, the patient underwent a left nephrectomy, regional lymphadenectomy, and excision of metastatic RV tumor with bovine patch reconstruction. Final pathology reported invasive urothelial carcinoma in the left kidney with involvement of regional para-aortic lymph nodes and metastatic tumor in the RV (T4N3M1, AJCC 8(th) edition). The patient did well postoperatively and completed adjuvant Cisplatin-Gemcitabine systemic chemotherapy. This is an important addition to the literature as it highlights the aggressive and heterogeneous nature of urothelial carcinoma and the utility of cardiac MRI in surgical planning. Wolters Kluwer - Medknow 2022 2022-01-20 /pmc/articles/PMC8815341/ /pubmed/35197710 http://dx.doi.org/10.4103/UA.UA_157_20 Text en Copyright: © 2022 Urology Annals https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Helman, Talia A.
Imam, Ahmad Saeed
Espino-Grosso, Pedro
Patel, Trushar
Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title_full Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title_fullStr Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title_full_unstemmed Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title_short Upper tract urothelial carcinoma with Oligometastasis to the right ventricle, surgical considerations, and management
title_sort upper tract urothelial carcinoma with oligometastasis to the right ventricle, surgical considerations, and management
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815341/
https://www.ncbi.nlm.nih.gov/pubmed/35197710
http://dx.doi.org/10.4103/UA.UA_157_20
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