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MicroRNA-mediated bioengineering for climate-resilience in crops

Global projections on the climate change and the dynamic environmental perturbations indicate severe impacts on food security in general, and crop yield, vigor and the quality of produce in particular. Sessile plants respond to environmental challenges such as salt, drought, temperature, heavy metal...

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Detalles Bibliográficos
Autores principales: Patil, Suraj, Joshi, Shrushti, Jamla, Monica, Zhou, Xianrong, Taherzadeh, Mohammad J, Suprasanna, Penna, Kumar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815627/
https://www.ncbi.nlm.nih.gov/pubmed/34747296
http://dx.doi.org/10.1080/21655979.2021.1997244
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author Patil, Suraj
Joshi, Shrushti
Jamla, Monica
Zhou, Xianrong
Taherzadeh, Mohammad J
Suprasanna, Penna
Kumar, Vinay
author_facet Patil, Suraj
Joshi, Shrushti
Jamla, Monica
Zhou, Xianrong
Taherzadeh, Mohammad J
Suprasanna, Penna
Kumar, Vinay
author_sort Patil, Suraj
collection PubMed
description Global projections on the climate change and the dynamic environmental perturbations indicate severe impacts on food security in general, and crop yield, vigor and the quality of produce in particular. Sessile plants respond to environmental challenges such as salt, drought, temperature, heavy metals at transcriptional and/or post-transcriptional levels through the stress-regulated network of pathways including transcription factors, proteins and the small non-coding endogenous RNAs. Amongs these, the miRNAs have gained unprecedented attention in recent years as key regulators for modulating gene expression in plants under stress. Hence, tailoring of miRNAs and their target pathways presents a promising strategy for developing multiple stress-tolerant crops. Plant stress tolerance has been successfully achieved through the over expression of microRNAs such as Os-miR408, Hv-miR82 for drought tolerance; OsmiR535A and artificial DST miRNA for salinity tolerance; and OsmiR535 and miR156 for combined drought and salt stress. Examples of miR408 overexpression also showed improved efficiency of irradiation utilization and carbon dioxide fixation in crop plants. Through this review, we present the current understanding about plant miRNAs, their roles in plant growth and stress-responses, the modern toolbox for identification, characterization and validation of miRNAs and their target genes including in silico tools, machine learning and artificial intelligence. Various approaches for up-regulation or knock-out of miRNAs have been discussed. The main emphasis has been given to the exploration of miRNAs for development of bioengineered climate-smart crops that can withstand changing climates and stressful environments, including combination of stresses, with very less or no yield penalties.
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spelling pubmed-88156272022-02-05 MicroRNA-mediated bioengineering for climate-resilience in crops Patil, Suraj Joshi, Shrushti Jamla, Monica Zhou, Xianrong Taherzadeh, Mohammad J Suprasanna, Penna Kumar, Vinay Bioengineered Review Global projections on the climate change and the dynamic environmental perturbations indicate severe impacts on food security in general, and crop yield, vigor and the quality of produce in particular. Sessile plants respond to environmental challenges such as salt, drought, temperature, heavy metals at transcriptional and/or post-transcriptional levels through the stress-regulated network of pathways including transcription factors, proteins and the small non-coding endogenous RNAs. Amongs these, the miRNAs have gained unprecedented attention in recent years as key regulators for modulating gene expression in plants under stress. Hence, tailoring of miRNAs and their target pathways presents a promising strategy for developing multiple stress-tolerant crops. Plant stress tolerance has been successfully achieved through the over expression of microRNAs such as Os-miR408, Hv-miR82 for drought tolerance; OsmiR535A and artificial DST miRNA for salinity tolerance; and OsmiR535 and miR156 for combined drought and salt stress. Examples of miR408 overexpression also showed improved efficiency of irradiation utilization and carbon dioxide fixation in crop plants. Through this review, we present the current understanding about plant miRNAs, their roles in plant growth and stress-responses, the modern toolbox for identification, characterization and validation of miRNAs and their target genes including in silico tools, machine learning and artificial intelligence. Various approaches for up-regulation or knock-out of miRNAs have been discussed. The main emphasis has been given to the exploration of miRNAs for development of bioengineered climate-smart crops that can withstand changing climates and stressful environments, including combination of stresses, with very less or no yield penalties. Taylor & Francis 2021-12-09 /pmc/articles/PMC8815627/ /pubmed/34747296 http://dx.doi.org/10.1080/21655979.2021.1997244 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Patil, Suraj
Joshi, Shrushti
Jamla, Monica
Zhou, Xianrong
Taherzadeh, Mohammad J
Suprasanna, Penna
Kumar, Vinay
MicroRNA-mediated bioengineering for climate-resilience in crops
title MicroRNA-mediated bioengineering for climate-resilience in crops
title_full MicroRNA-mediated bioengineering for climate-resilience in crops
title_fullStr MicroRNA-mediated bioengineering for climate-resilience in crops
title_full_unstemmed MicroRNA-mediated bioengineering for climate-resilience in crops
title_short MicroRNA-mediated bioengineering for climate-resilience in crops
title_sort microrna-mediated bioengineering for climate-resilience in crops
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815627/
https://www.ncbi.nlm.nih.gov/pubmed/34747296
http://dx.doi.org/10.1080/21655979.2021.1997244
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