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Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five

Introduction: Elderly patients have increased morbidity and mortality compared to younger patients due to existing comorbid diseases and chronic immunosuppression. Therefore, the option of kidney transplantation for renal replacement therapy in elderly patients is still being controversial. Our aim...

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Autores principales: Yilmaz, Gulay, Ozdemir, Ebru, Yildar, Murat, Karayagiz, Hamit, Berber, Ibrahim, Cakir, Ulkem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815706/
https://www.ncbi.nlm.nih.gov/pubmed/35154914
http://dx.doi.org/10.7759/cureus.20913
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author Yilmaz, Gulay
Ozdemir, Ebru
Yildar, Murat
Karayagiz, Hamit
Berber, Ibrahim
Cakir, Ulkem
author_facet Yilmaz, Gulay
Ozdemir, Ebru
Yildar, Murat
Karayagiz, Hamit
Berber, Ibrahim
Cakir, Ulkem
author_sort Yilmaz, Gulay
collection PubMed
description Introduction: Elderly patients have increased morbidity and mortality compared to younger patients due to existing comorbid diseases and chronic immunosuppression. Therefore, the option of kidney transplantation for renal replacement therapy in elderly patients is still being controversial. Our aim in this study was to evaluate graft function, graft and patient survival, and associated factors in kidney transplant recipients over 65 years of age, at 11 years of follow-up. Methods: The study included 53 patients aged 65-76 years, out of a total of 1319 patients who underwent live kidney transplantation in the Organ Transplant Center of Acibadem International Hospital between October 2010 and July 2021. Demographic characteristics and creatinine values were recorded. Graft survival rates and patient survival rates at one, three, and five years were analyzed. Results: Fifty-three patients, 14 female, 39 male, aged 65-76 years were included in the study. The follow-up period of the patients was 7-125 months. During the follow-up, 20 patients died. Graft loss occurred in two of 20 patients who died, and 18 patients died with working grafts. Graft loss developed in two of the 33 surviving patients. In the whole group, one-, three-, and five-year patient survival rates were 94%, 81%, and 76%, respectively. Conclusion: These results emphasize that kidney transplantation is a viable treatment option in elderly patients who have been well evaluated before kidney transplantation.
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spelling pubmed-88157062022-02-10 Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five Yilmaz, Gulay Ozdemir, Ebru Yildar, Murat Karayagiz, Hamit Berber, Ibrahim Cakir, Ulkem Cureus Nephrology Introduction: Elderly patients have increased morbidity and mortality compared to younger patients due to existing comorbid diseases and chronic immunosuppression. Therefore, the option of kidney transplantation for renal replacement therapy in elderly patients is still being controversial. Our aim in this study was to evaluate graft function, graft and patient survival, and associated factors in kidney transplant recipients over 65 years of age, at 11 years of follow-up. Methods: The study included 53 patients aged 65-76 years, out of a total of 1319 patients who underwent live kidney transplantation in the Organ Transplant Center of Acibadem International Hospital between October 2010 and July 2021. Demographic characteristics and creatinine values were recorded. Graft survival rates and patient survival rates at one, three, and five years were analyzed. Results: Fifty-three patients, 14 female, 39 male, aged 65-76 years were included in the study. The follow-up period of the patients was 7-125 months. During the follow-up, 20 patients died. Graft loss occurred in two of 20 patients who died, and 18 patients died with working grafts. Graft loss developed in two of the 33 surviving patients. In the whole group, one-, three-, and five-year patient survival rates were 94%, 81%, and 76%, respectively. Conclusion: These results emphasize that kidney transplantation is a viable treatment option in elderly patients who have been well evaluated before kidney transplantation. Cureus 2022-01-03 /pmc/articles/PMC8815706/ /pubmed/35154914 http://dx.doi.org/10.7759/cureus.20913 Text en Copyright © 2022, Yilmaz et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Nephrology
Yilmaz, Gulay
Ozdemir, Ebru
Yildar, Murat
Karayagiz, Hamit
Berber, Ibrahim
Cakir, Ulkem
Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title_full Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title_fullStr Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title_full_unstemmed Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title_short Graft and Patient Survival in Kidney Transplant Recipients Over the Age of Sıxty-Five
title_sort graft and patient survival in kidney transplant recipients over the age of sıxty-five
topic Nephrology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815706/
https://www.ncbi.nlm.nih.gov/pubmed/35154914
http://dx.doi.org/10.7759/cureus.20913
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