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An Unusual Presentation of Diffuse Large B-Cell Lymphoma
Hyperlactemia is a rare and potentially fatal complication of hematologic malignancies, as well as an oncological emergency, which requires a fast diagnosis and early therapeutic management, as these interventions may alter disease prognosis. Herein, we present a case of secondary liver-biopsy-confi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815724/ https://www.ncbi.nlm.nih.gov/pubmed/35154918 http://dx.doi.org/10.7759/cureus.20927 |
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author | Gkoufa, Aikaterini Georgakopoulou, Vasiliki E Lakiotaki, Eleftheria Cholongitas, Evangelos |
author_facet | Gkoufa, Aikaterini Georgakopoulou, Vasiliki E Lakiotaki, Eleftheria Cholongitas, Evangelos |
author_sort | Gkoufa, Aikaterini |
collection | PubMed |
description | Hyperlactemia is a rare and potentially fatal complication of hematologic malignancies, as well as an oncological emergency, which requires a fast diagnosis and early therapeutic management, as these interventions may alter disease prognosis. Herein, we present a case of secondary liver-biopsy-confirmed diffuse large B-cell lymphoma (DLBCL), presented with elevated liver enzymes and lactic acidosis, without depicted hepatic lesions, hepatosplenomegaly, or enlarged lymph nodes on computed tomography. This case confirms the poor prognosis of cases with delayed diagnostic intervention and highlights the importance of early clinical suspicion, liver biopsy, and prompt treatment initiation. |
format | Online Article Text |
id | pubmed-8815724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88157242022-02-10 An Unusual Presentation of Diffuse Large B-Cell Lymphoma Gkoufa, Aikaterini Georgakopoulou, Vasiliki E Lakiotaki, Eleftheria Cholongitas, Evangelos Cureus Internal Medicine Hyperlactemia is a rare and potentially fatal complication of hematologic malignancies, as well as an oncological emergency, which requires a fast diagnosis and early therapeutic management, as these interventions may alter disease prognosis. Herein, we present a case of secondary liver-biopsy-confirmed diffuse large B-cell lymphoma (DLBCL), presented with elevated liver enzymes and lactic acidosis, without depicted hepatic lesions, hepatosplenomegaly, or enlarged lymph nodes on computed tomography. This case confirms the poor prognosis of cases with delayed diagnostic intervention and highlights the importance of early clinical suspicion, liver biopsy, and prompt treatment initiation. Cureus 2022-01-04 /pmc/articles/PMC8815724/ /pubmed/35154918 http://dx.doi.org/10.7759/cureus.20927 Text en Copyright © 2022, Gkoufa et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Gkoufa, Aikaterini Georgakopoulou, Vasiliki E Lakiotaki, Eleftheria Cholongitas, Evangelos An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title | An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title_full | An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title_fullStr | An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title_full_unstemmed | An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title_short | An Unusual Presentation of Diffuse Large B-Cell Lymphoma |
title_sort | unusual presentation of diffuse large b-cell lymphoma |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815724/ https://www.ncbi.nlm.nih.gov/pubmed/35154918 http://dx.doi.org/10.7759/cureus.20927 |
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