Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders

Obesity and type 2 diabetes are associated with cognitive dysfunction. Because the hypothalamus is implicated in energy balance control and memory disorders, we hypothesized that specific neurons in this brain region are at the interface of metabolism and cognition. Acute obesogenic diet administrat...

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Detalles Bibliográficos
Autores principales: Ramírez, Sara, Haddad-Tóvolli, Roberta, Radosevic, Marija, Toledo, Miriam, Pané, Adriana, Alcolea, Daniel, Ribas, Vicent, Milà-Guasch, Maria, Pozo, Macarena, Obri, Arnaud, Eyre, Elena, Gómez-Valadés, Alicia G., Chivite, Iñigo, Van Eeckhout, Tomas, Zalachoras, Ioannis, Altirriba, Jordi, Bauder, Corinna, Imbernón, Mónica, Garrabou, Gloria, Garcia-Ruiz, Carmen, Nogueiras, Rubén, Soto, David, Gasull, Xavier, Sandi, Carmen, Brüning, Jens C., Fortea, Juan, Jiménez, Amanda, Fernández-Checa, José C., Claret, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815774/
https://www.ncbi.nlm.nih.gov/pubmed/35108514
http://dx.doi.org/10.1016/j.cmet.2021.12.023

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