A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity

BACKGROUND: The severity of COVID-19 after SARS-CoV-2 infection is unpredictable. Angiotensin-converting enzyme-2 (ACE2) is the receptor responsible for coronavirus binding, while subsequent cell entry relies on priming by the serine protease TMPRSS2 (transmembrane protease, serine 2). Although reni...

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Detalles Bibliográficos
Autores principales: Akin, Sakir, Schriek, Paula, van Nieuwkoop, Cees, Neuman, Rugina I., Meynaar, Iwan, van Helden, Erik J., Bouazzaoui, Hassan El, Baak, Remon, Veuger, Marjan, Mairuhu, Ronne A.T.A., van den Berg, Lettie, van Driel, Vincent, Visser, Loes E., de Jonge, Evert, Garrelds, Ingrid M., Duynstee, Johannes F.A.B., van Rooden, Jan Kees, Ludikhuize, Jeroen, Verdonk, Koen, Caliskan, Kadir, Jansen, Tim, van Schaik, Ron H.N., Danser, A.H. Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815849/
https://www.ncbi.nlm.nih.gov/pubmed/34862332
http://dx.doi.org/10.1097/HJH.0000000000003054

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