Atractylenolide I Ameliorates Acetaminophen-Induced Acute Liver Injury via the TLR4/MAPKs/NF-κB Signaling Pathways

Background: Acetaminophen (APAP) overdose results in the production of reactive oxygen species (ROS), induces hepatocyte necrosis, and leads to acute liver failure. Atractylenolide I (AO-I), a phytochemical found in Atractylodes macrocephala Koidz, is known to exhibit antioxidant activity. However,...

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Detalles Bibliográficos
Autores principales: Du, Zhongyan, Ma, Zhimei, Lai, Shanglei, Ding, Qinchao, Hu, Ziyi, Yang, Wenwen, Qian, Qianyu, Zhu, Linwensi, Dou, Xiaobing, Li, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815859/
https://www.ncbi.nlm.nih.gov/pubmed/35126160
http://dx.doi.org/10.3389/fphar.2022.797499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815859/
https://www.ncbi.nlm.nih.gov/pubmed/35126160
http://dx.doi.org/10.3389/fphar.2022.797499

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