Cargando…

Lung and blood early biomarkers for host-directed tuberculosis therapies: Secondary outcome measures from a randomized controlled trial

BACKGROUND: Current tuberculosis treatments leave most patients with bronchiectasis and fibrosis, permanent conditions that impair lung function and increase all-cause post-TB mortality. Host-directed therapies (HDTs) may reduce lung inflammation and hasten eradication of infection. Biomarkers can a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wallis, Robert S., Ginindza, Sibuse, Beattie, Trevor, Arjun, Nishanee, Likoti, Morongwe, Sebe, Modulakgotla, Edward, Vinodh A., Rassool, Mohammed, Ahmed, Khatija, Fielding, Katherine, Ahidjo, Bintou A., Vangu, Mboyo D. T., Churchyard, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815935/ https://www.ncbi.nlm.nih.gov/pubmed/35120127 http://dx.doi.org/10.1371/journal.pone.0252097

Ejemplares similares

Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial
por: Wallis, Robert S, et al.
Publicado: (2021)

Missed Opportunities for TB Investigation in Primary Care Clinics in South Africa: Experience from the XTEND Trial
por: Chihota, Violet N., et al.
Publicado: (2015)

Pulmonary restriction predicts long-term pulmonary impairment in people with HIV and tuberculosis
por: Auld, Sara C., et al.
Publicado: (2021)

Lung function and collagen 1a levels are associated with changes in 6 min walk test distance during treatment of TB among HIV-infected adults: a prospective cohort study
por: Baik, Yeonsoo, et al.
Publicado: (2023)

Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
por: Auld, Sara C, et al.
Publicado: (2020)

Efficacy of full-fat milk and diluted lemon juice in reducing infra-cardiac activity of (99m)Tc sestamibi during myocardial perfusion imaging
por: Purbhoo, Khushica, et al.
Publicado: (2015)

Evaluation of technetium-99m metastable nanocolloid as an imaging agent for performing milk scans
por: Evbuomwan, Osayande, et al.
Publicado: (2019)

Quantitative Assessment of Radionuclide Uptake and Positron Emission Tomography-computed Tomography Image Contrast
por: Francis, Hasford, et al.
Publicado: (2016)

Phosphodiesterase inhibitors as adjunctive therapies for tuberculosis
por: Ahidjo, Bintou Ahmadou, et al.
Publicado: (2016)

Myocardial Perfusion SPECT Imaging in Dextrocardia with Situs Inversus: A Case Report
por: Ayeni, Olusegun Akinwale, et al.
Publicado: (2016)

Does dipyridamole-induced ischaemia affect NT-proBNP secretion?
por: De Greef, Jacques, et al.
Publicado: (2007)

Potentiation of the Abscopal Effect by Modulated Electro-Hyperthermia in Locally Advanced Cervical Cancer Patients
por: Minnaar, Carrie Anne, et al.
Publicado: (2020)

Defining Characteristics of Nodal Disease on PET/CT Scans in Patients With HIV-Positive and -Negative Locally Advanced Cervical Cancer in South Africa
por: Minnaar, Carrie Anne, et al.
Publicado: (2019)

NT-proBNP and the diagnosis of exercise-induced myocardial ischaemia
por: De Greef, Jacques, et al.
Publicado: (2008)

Effect of Radionuclide Activity Concentration on PET-CT Image Uniformity
por: Hasford, Francis, et al.
Publicado: (2016)

Failure of A Novel, Rapid Antigen and Antibody Combination Test to Detect Antigen-Positive HIV Infection in African Adults with Early HIV Infection
por: Kilembe, William, et al.
Publicado: (2012)

Implementation and Operational Research: What Happens After a Negative Test for Tuberculosis? Evaluating Adherence to TB Diagnostic Algorithms in South African Primary Health Clinics
por: McCarthy, K. M., et al.
Publicado: (2016)

Effectiveness of an “Exclusive Intervention Strategy” to increase medical male circumcision uptake among men aged 25–49 years in South Africa
por: Grund, Jonathan M., et al.
Publicado: (2018)

Critical Appraisal of Radionuclide Calibrators and Gamma Cameras Prior to Lutetium-177 Internal Dosimetry at Two South African Hospitals
por: Van Wyk, Bronwin P., et al.
Publicado: (2022)

Description of adverse events among adult men following voluntary medical male circumcision: Findings from a circumcision programme in two provinces of South Africa
por: Muchiri, Evans, et al.
Publicado: (2021)

The effect of modulated electro-hyperthermia on local disease control in HIV-positive and -negative cervical cancer women in South Africa: Early results from a phase III randomised controlled trial
por: Minnaar, Carrie Anne, et al.
Publicado: (2019)

Empiric tuberculosis treatment in South African primary health care facilities - for whom, where, when and why: Implications for the development of tuberculosis diagnostic tests
por: McCarthy, Kerrigan, et al.
Publicado: (2018)

Trends in silicosis prevalence and the healthy worker effect among gold miners in South Africa: a prevalence study with follow up of employment status
por: Knight, David, et al.
Publicado: (2015)

Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners
por: Chihota, Violet N., et al.
Publicado: (2022)

Predictors of silicosis and variation in prevalence across mines among employed gold miners in South Africa
por: Knight, Dave, et al.
Publicado: (2020)

Comparing QuantiFERON-TB Gold Plus with QuantiFERON-TB Gold in-tube for diagnosis of latent tuberculosis infection among highly TB exposed gold miners in South Africa
por: Ntshiqa, Thobani, et al.
Publicado: (2022)

Tuberculosis Infectiousness and Host Susceptibility
por: Turner, Richard D, et al.
Publicado: (2017)

Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant pulmonary tuberculosis: a multicentre, open-label, partially randomised, phase 2b trial
por: Tweed, Conor D, et al.
Publicado: (2019)

An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19
por: Chimoyi, Lucy, et al.
Publicado: (2020)

Anterior and posterior segment parameters measured with Fourier domain optical coherence tomography in photopic and scotopic conditions
por: Rampersad, Nishanee, et al.
Publicado: (2016)

Repeatability and reproducibility of retinal nerve fibre layer thickness measurements with the iVue-100 optical coherence tomographer
por: Rampersad, Nishanee, et al.
Publicado: (2018)

Motivation for postgraduate studies by nonacademic optometrists: A case study at a South African university
por: Hansraj, Rekha, et al.
Publicado: (2022)

Second-Line Antiretroviral Therapy in a Workplace and Community-Based Treatment Programme in South Africa: Determinants of Virological Outcome
por: Johnston, Victoria, et al.
Publicado: (2012)

Low haemoglobin predicts early mortality among adults starting antiretroviral therapy in an HIV care programme in South Africa: a cohort study
por: Russell, Elizabeth C, et al.
Publicado: (2010)

Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis
por: Maiga, Mamoudou, et al.
Publicado: (2015)

Erratum to “Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis” [EBioMedicine 2 (8), August 2015, 868–873]
por: Maiga, Mamoudou, et al.
Publicado: (2015)

"That is why I stopped the ART": Patients' & providers' perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme
por: Dahab, Mison, et al.
Publicado: (2008)

Cataract surgery outcomes: comparison of the extracapsular cataract extraction and manual small incision cataract surgery techniques
por: Zitha, Amukelani Jimmy, et al.
Publicado: (2022)

The patient costs of care for those with TB and HIV: a cross-sectional study from South Africa
por: Mudzengi, Don, et al.
Publicado: (2017)

Historical Development, Applications and Advances in Materials Used in Spectacle Lenses and Contact Lenses
por: Pillay, Rayishnee, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6ud6f6o3tqd064sgimi1mikf7p