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The estimates of effective population size based on linkage disequilibrium are virtually unaffected by natural selection
The effective population size (N(e)) is a key parameter to quantify the magnitude of genetic drift and inbreeding, with important implications in human evolution. The increasing availability of high-density genetic markers allows the estimation of historical changes in N(e) across time using measure...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815936/ https://www.ncbi.nlm.nih.gov/pubmed/35077457 http://dx.doi.org/10.1371/journal.pgen.1009764 |