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Adrenal suppression in patients with chronic obstructive pulmonary disease treated with glucocorticoids: Role of specific glucocorticoid receptor polymorphisms

BACKGROUND: Single-nucleotide polymorphisms (SNPs) of the glucocorticoid receptor (GR) gene NR3C1 have been associated with an altered sensitivity to glucocorticoids, and thus may alter the therapeutic effects of glucocorticoids. We investigated the prevalence of adrenal suppression after treatment...

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Detalles Bibliográficos
Autores principales:	Sivapalan, Pradeesh, Borresen, Stina Willemoes, Eklöf, Josefin, Klose, Marianne, Holm, Freja S., Feldt-Rasmussen, Ulla, Rossing, Maria, Jørgensen, Niklas R., Marvig, Rasmus L., Saeed, Mohamad Isam, Wilcke, Torgny, Seersholm, Niels, Mathioudakis, Alexander G., Vestbo, Jørgen, Jensen, Jens-Ulrik Stæhr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815987/ https://www.ncbi.nlm.nih.gov/pubmed/35120172 http://dx.doi.org/10.1371/journal.pone.0262898

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