P2X4 and P2X7 are essential players in basal T cell activity and Ca(2+) signaling milliseconds after T cell activation

Initial T cell activation is triggered by the formation of highly dynamic, spatiotemporally restricted Ca(2+) microdomains. Purinergic signaling is known to be involved in Ca(2+) influx in T cells at later stages compared to the initial microdomain formation. Using a high-resolution Ca(2+) live-cell...

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Detalles Bibliográficos
Autores principales: Brock, Valerie J., Wolf, Insa M. A., Er-Lukowiak, Marco, Lory, Niels, Stähler, Tobias, Woelk, Lena-Marie, Mittrücker, Hans-Willi, Müller, Christa E., Koch-Nolte, Friedrich, Rissiek, Björn, Werner, René, Guse, Andreas H., Diercks, Björn-Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816335/
https://www.ncbi.nlm.nih.gov/pubmed/35119925
http://dx.doi.org/10.1126/sciadv.abl9770

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