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PARP inhibitors as a radiosensitizer: a future promising approach in prostate cancer?

Poly (ADP-ribose) polymerase (PARP) inhibitors (iPARPs) have shown efficacy in homologous recombination (HR) deficiency patients with advanced castration resistant prostate cancer and have shown a radiosensitizing effect in preclinical and early clinical trials. Preclinical data in prostate cancer c...

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Detalles Bibliográficos
Autores principales: Angel, Martin, Zarba, Martin, Sade, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816501/
https://www.ncbi.nlm.nih.gov/pubmed/35211207
http://dx.doi.org/10.3332/ecancer.2021.ed118