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Robotic automation of droplet microfluidics
Droplet microfluidics enables powerful analytic capabilities but often requires workflows involving macro- and microfluidic processing steps that are cumbersome to perform manually. Here, we demonstrate the automation of droplet microfluidics with commercial fluid-handling robotics. The workflows in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816516/ https://www.ncbi.nlm.nih.gov/pubmed/35145570 http://dx.doi.org/10.1063/5.0064265 |
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author | Tran, Tuan M. Kim, Samuel C. Modavi, Cyrus Abate, Adam R. |
author_facet | Tran, Tuan M. Kim, Samuel C. Modavi, Cyrus Abate, Adam R. |
author_sort | Tran, Tuan M. |
collection | PubMed |
description | Droplet microfluidics enables powerful analytic capabilities but often requires workflows involving macro- and microfluidic processing steps that are cumbersome to perform manually. Here, we demonstrate the automation of droplet microfluidics with commercial fluid-handling robotics. The workflows incorporate common microfluidic devices including droplet generators, mergers, and sorters and utilize the robot's native capabilities for thermal control, incubation, and plate scanning. The ability to automate microfluidic devices using commercial fluid handling will speed up the integration of these methods into biological workflows. |
format | Online Article Text |
id | pubmed-8816516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-88165162022-02-09 Robotic automation of droplet microfluidics Tran, Tuan M. Kim, Samuel C. Modavi, Cyrus Abate, Adam R. Biomicrofluidics Regular Articles Droplet microfluidics enables powerful analytic capabilities but often requires workflows involving macro- and microfluidic processing steps that are cumbersome to perform manually. Here, we demonstrate the automation of droplet microfluidics with commercial fluid-handling robotics. The workflows incorporate common microfluidic devices including droplet generators, mergers, and sorters and utilize the robot's native capabilities for thermal control, incubation, and plate scanning. The ability to automate microfluidic devices using commercial fluid handling will speed up the integration of these methods into biological workflows. AIP Publishing LLC 2022-02-03 /pmc/articles/PMC8816516/ /pubmed/35145570 http://dx.doi.org/10.1063/5.0064265 Text en © 2022 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Regular Articles Tran, Tuan M. Kim, Samuel C. Modavi, Cyrus Abate, Adam R. Robotic automation of droplet microfluidics |
title | Robotic automation of droplet microfluidics |
title_full | Robotic automation of droplet microfluidics |
title_fullStr | Robotic automation of droplet microfluidics |
title_full_unstemmed | Robotic automation of droplet microfluidics |
title_short | Robotic automation of droplet microfluidics |
title_sort | robotic automation of droplet microfluidics |
topic | Regular Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816516/ https://www.ncbi.nlm.nih.gov/pubmed/35145570 http://dx.doi.org/10.1063/5.0064265 |
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