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Recent Advances in the Development of Noble Metal NPs for Cancer Therapy

With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanom...

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Detalles Bibliográficos
Autores principales: Zhao, Rui, Xiang, Jia, Wang, Bo, Chen, Lin, Tan, Songwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816609/
https://www.ncbi.nlm.nih.gov/pubmed/35126483
http://dx.doi.org/10.1155/2022/2444516
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author Zhao, Rui
Xiang, Jia
Wang, Bo
Chen, Lin
Tan, Songwen
author_facet Zhao, Rui
Xiang, Jia
Wang, Bo
Chen, Lin
Tan, Songwen
author_sort Zhao, Rui
collection PubMed
description With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanomedicines that can be used for cancer treatment based on the morphology, physical and chemical properties, mechanism of action, and toxicological studies of noble metal nanoparticles. Furthermore, the integration of diagnosis and treatment, hyperthermia, cytotoxicity research, and drug delivery system based on the study of noble metal nanoparticles can be used as effective means for cancer treatment. This article focuses on the analysis of noble metal nanoparticles that are widely used in the treatment of cancer, such as gold nanoparticles, silver nanoparticles, platinum nanoparticles, and palladium nanoparticles. The various methods and mechanisms of action of noble metal nanoparticles in the treatment of cancer are objectively summarized in detail. Based on the research on the therapeutic safety and toxicity of noble metal nanoparticles, the development prospect of noble metal nanoparticles in the future clinical application is prospected.
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spelling pubmed-88166092022-02-05 Recent Advances in the Development of Noble Metal NPs for Cancer Therapy Zhao, Rui Xiang, Jia Wang, Bo Chen, Lin Tan, Songwen Bioinorg Chem Appl Review Article With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanomedicines that can be used for cancer treatment based on the morphology, physical and chemical properties, mechanism of action, and toxicological studies of noble metal nanoparticles. Furthermore, the integration of diagnosis and treatment, hyperthermia, cytotoxicity research, and drug delivery system based on the study of noble metal nanoparticles can be used as effective means for cancer treatment. This article focuses on the analysis of noble metal nanoparticles that are widely used in the treatment of cancer, such as gold nanoparticles, silver nanoparticles, platinum nanoparticles, and palladium nanoparticles. The various methods and mechanisms of action of noble metal nanoparticles in the treatment of cancer are objectively summarized in detail. Based on the research on the therapeutic safety and toxicity of noble metal nanoparticles, the development prospect of noble metal nanoparticles in the future clinical application is prospected. Hindawi 2022-01-28 /pmc/articles/PMC8816609/ /pubmed/35126483 http://dx.doi.org/10.1155/2022/2444516 Text en Copyright © 2022 Rui Zhao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhao, Rui
Xiang, Jia
Wang, Bo
Chen, Lin
Tan, Songwen
Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title_full Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title_fullStr Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title_full_unstemmed Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title_short Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
title_sort recent advances in the development of noble metal nps for cancer therapy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816609/
https://www.ncbi.nlm.nih.gov/pubmed/35126483
http://dx.doi.org/10.1155/2022/2444516
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