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Recent Advances in the Development of Noble Metal NPs for Cancer Therapy
With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanom...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816609/ https://www.ncbi.nlm.nih.gov/pubmed/35126483 http://dx.doi.org/10.1155/2022/2444516 |
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author | Zhao, Rui Xiang, Jia Wang, Bo Chen, Lin Tan, Songwen |
author_facet | Zhao, Rui Xiang, Jia Wang, Bo Chen, Lin Tan, Songwen |
author_sort | Zhao, Rui |
collection | PubMed |
description | With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanomedicines that can be used for cancer treatment based on the morphology, physical and chemical properties, mechanism of action, and toxicological studies of noble metal nanoparticles. Furthermore, the integration of diagnosis and treatment, hyperthermia, cytotoxicity research, and drug delivery system based on the study of noble metal nanoparticles can be used as effective means for cancer treatment. This article focuses on the analysis of noble metal nanoparticles that are widely used in the treatment of cancer, such as gold nanoparticles, silver nanoparticles, platinum nanoparticles, and palladium nanoparticles. The various methods and mechanisms of action of noble metal nanoparticles in the treatment of cancer are objectively summarized in detail. Based on the research on the therapeutic safety and toxicity of noble metal nanoparticles, the development prospect of noble metal nanoparticles in the future clinical application is prospected. |
format | Online Article Text |
id | pubmed-8816609 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-88166092022-02-05 Recent Advances in the Development of Noble Metal NPs for Cancer Therapy Zhao, Rui Xiang, Jia Wang, Bo Chen, Lin Tan, Songwen Bioinorg Chem Appl Review Article With the development of nanotechnology, noble metal nanoparticles are widely used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. In recent years, researchers have designed and synthesized a large number of nanomedicines that can be used for cancer treatment based on the morphology, physical and chemical properties, mechanism of action, and toxicological studies of noble metal nanoparticles. Furthermore, the integration of diagnosis and treatment, hyperthermia, cytotoxicity research, and drug delivery system based on the study of noble metal nanoparticles can be used as effective means for cancer treatment. This article focuses on the analysis of noble metal nanoparticles that are widely used in the treatment of cancer, such as gold nanoparticles, silver nanoparticles, platinum nanoparticles, and palladium nanoparticles. The various methods and mechanisms of action of noble metal nanoparticles in the treatment of cancer are objectively summarized in detail. Based on the research on the therapeutic safety and toxicity of noble metal nanoparticles, the development prospect of noble metal nanoparticles in the future clinical application is prospected. Hindawi 2022-01-28 /pmc/articles/PMC8816609/ /pubmed/35126483 http://dx.doi.org/10.1155/2022/2444516 Text en Copyright © 2022 Rui Zhao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Zhao, Rui Xiang, Jia Wang, Bo Chen, Lin Tan, Songwen Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title | Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title_full | Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title_fullStr | Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title_full_unstemmed | Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title_short | Recent Advances in the Development of Noble Metal NPs for Cancer Therapy |
title_sort | recent advances in the development of noble metal nps for cancer therapy |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816609/ https://www.ncbi.nlm.nih.gov/pubmed/35126483 http://dx.doi.org/10.1155/2022/2444516 |
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