A mitochondria cluster at the proximal axon initial segment controls axodendritic TAU trafficking in rodent primary and human iPSC-derived neurons

Loss of neuronal polarity and missorting of the axonal microtubule-associated-protein TAU are hallmarks of Alzheimer’s disease (AD) and related tauopathies. Impairment of mitochondrial function is causative for various mitochondriopathies, but the role of mitochondria in tauopathies and in axonal TA...

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Detalles Bibliográficos
Autores principales: Tjiang, Noah, Zempel, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816743/
https://www.ncbi.nlm.nih.gov/pubmed/35119496
http://dx.doi.org/10.1007/s00018-022-04150-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816743/
https://www.ncbi.nlm.nih.gov/pubmed/35119496
http://dx.doi.org/10.1007/s00018-022-04150-3

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