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PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis

Phosphoglycerate kinase 1 (PGK1) has complicated and multiple functions in cancer occurrence, tumor progression and drug resistance. Sorafenib is the first-line treatment targeted drug for patients with kidney renal clear cell carcinoma (KIRC) as a tyrosine kinase inhibitor, but sorafenib resistance...

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Detalles Bibliográficos
Autores principales:	He, Yu, Wang, Xixi, Lu, Weiliang, Zhang, Dan, Huang, Lan, Luo, Yang, Xiong, Li, Li, Haocheng, Zhang, Peng, Li, Qiu, Liang, Shufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816910/ https://www.ncbi.nlm.nih.gov/pubmed/35121728 http://dx.doi.org/10.1038/s41419-022-04576-4

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