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Long noncoding RNA RP11-241J12.3 targeting pyruvate carboxylase promotes hepatocellular carcinoma aggressiveness by disrupting pyruvate metabolism and the DNA mismatch repair system

Accumulating evidence indicates that hepatitis B virus X protein (HBx) plays a key role in HBV-related hepatocellular carcinoma (HCC) aggressiveness; however, the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which participate in the regulation of diverse biological p...

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Detalles Bibliográficos
Autores principales: Cheng, Liuliu, Hu, Shichuan, Ma, Jinhu, Shu, Yongheng, Chen, Yanwei, Zhang, Bin, Qi, Zhongbing, Wang, Yunmeng, Zhang, Yan, Zhang, Yuwei, Cheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816999/
https://www.ncbi.nlm.nih.gov/pubmed/35122182
http://dx.doi.org/10.1186/s43556-021-00065-w