Cargando…

Autophagy-competent mitochondrial translation elongation factor TUFM inhibits caspase-8-mediated apoptosis

Mitochondria support multiple cell functions, but an accumulation of dysfunctional or excessive mitochondria is detrimental to cells. We previously demonstrated that a defect in the autophagic removal of mitochondria, termed mitophagy, leads to the acceleration of apoptosis induced by herpesvirus pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Chang-Yong, Vo, Mai Tram, Nicholas, John, Choi, Young Bong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817016/ https://www.ncbi.nlm.nih.gov/pubmed/34511600 http://dx.doi.org/10.1038/s41418-021-00868-y

Ejemplares similares

Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction
por: Kim, Dasol, et al.
Publicado: (2021)

Herpesvirus Regulation of Selective Autophagy
por: Vo, Mai Tram, et al.
Publicado: (2021)

Silencing TUFM Inhibits Development of Monocrotaline-Induced Pulmonary Hypertension by Regulating Mitochondrial Autophagy via AMPK/mTOR Signal Pathway
por: Wei, Ruyuan, et al.
Publicado: (2022)

Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy
por: Kuo, Shu-Ming, et al.
Publicado: (2017)

TUFM-knockdown inhibits the migration and proliferation of gastrointestinal stromal tumor cells
por: Weng, Xiaoyuan, et al.
Publicado: (2020)

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagy
por: Vo, Mai Tram, et al.
Publicado: (2023)

Down-regulation of TUFM impairs host cell interaction and virulence by Paracoccidioides brasiliensis
por: Marcos, Caroline Maria, et al.
Publicado: (2019)

Glioblastoma-specific anti-TUFM nanobody for in-vitro immunoimaging and cancer stem cell targeting
por: Samec, Neja, et al.
Publicado: (2018)

Mitochondrial caspase keeps autophagy in flux
por: Short, Ben
Publicado: (2014)

EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex
por: Lei, Yu, et al.
Publicado: (2016)

Expression and clinicopathologic significance of TUFM and p53 for the normal–adenoma–carcinoma sequence in colorectal epithelia
por: Xi, Hong-Qing, et al.
Publicado: (2017)

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus
por: Vo, Mai Tram, et al.
Publicado: (2019)

Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis
por: Chung, Yuhyun, et al.
Publicado: (2018)

Caspase-8 is required for HSV-1-induced apoptosis and promotes effective viral particle release via autophagy inhibition
por: Marino-Merlo, Francesca, et al.
Publicado: (2022)

A New Caspase-8 Isoform Caspase-8s Increased Sensitivity to Apoptosis in Jurkat Cells
por: Xu, Zhifang, et al.
Publicado: (2009)

Conflict between Translation Initiation and Elongation in Vertebrate Mitochondrial Genomes
por: Xia, Xuhua, et al.
Publicado: (2007)

FUNDC1 protects against doxorubicin-induced cardiomyocyte PANoptosis through stabilizing mtDNA via interaction with TUFM
por: Bi, Yaguang, et al.
Publicado: (2022)

Proteasome inhibition attenuates rasfonin-induced autophagy concurring with the upregulation of caspase-dependent apoptosis
por: Yan, Siyuan, et al.
Publicado: (2016)

Bioinformatics and Translation Elongation
por: Xia, Xuhua
Publicado: (2018)

Shikonin promotes adriamycin-induced apoptosis by upregulating caspase-3 and caspase-8 in osteosarcoma
por: Yang, Qing, et al.
Publicado: (2017)

Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet
por: Cao, Li, et al.
Publicado: (2021)

Caspases: A Molecular Switch Node in the Crosstalk between Autophagy and Apoptosis
por: Wu, Haijian, et al.
Publicado: (2014)

Novel functional roles of caspase-related genes in the regulation of apoptosis and autophagy
por: Shin, Ju-Hyun, et al.
Publicado: (2016)

Inhibition of Eukaryotic Translation Elongation by Cycloheximide and Lactimidomycin
por: Schneider-Poetsch, Tilman, et al.
Publicado: (2010)

Nitric oxide-mediated apoptosis of neutrophils through caspase-8 and caspase-3-dependent mechanism
por: Dubey, Megha, et al.
Publicado: (2016)

GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell
por: Haque, Md Ezazul, et al.
Publicado: (2020)

Euglycemia in Diabetic Rats Leads to Reduced Liver Weight via Increased Autophagy and Apoptosis through Increased AMPK and Caspase-3 and Decreased mTOR Activities
por: Lee, Jun-Ho, et al.
Publicado: (2015)

Ethyl Gallate Induces Apoptosis of HL-60 Cells by Promoting the Expression of Caspases-8, -9, -3, Apoptosis-Inducing Factor and Endonuclease G
por: Kim, Woong-Hyun, et al.
Publicado: (2012)

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
por: Stupack, Dwayne G., et al.
Publicado: (2001)

Elongator: Transcriptional or translational regulator?
por: Glatt, Sebastian, et al.
Publicado: (2012)

Fenofibrate reduces cisplatin-induced apoptosis by inhibiting the p53/Puma/Caspase-9 pathway and the MAPK/Caspase-8 pathway rather than by promoting autophagy in murine renal proximal tubular cells
por: Kimura, Hideki, et al.
Publicado: (2022)

BECLIN-1-Mediated Autophagy Suppresses Silica Nanoparticle-Induced Testicular Toxicity via the Inhibition of Caspase 8-Mediated Cell Apoptosis in Leydig Cells
por: Zhang, Qianru, et al.
Publicado: (2022)

Autophagy enhances the replication of Peste des petits ruminants virus and inhibits caspase-dependent apoptosis in vitro
por: Yang, Bo, et al.
Publicado: (2018)

B7 Induces Apoptosis in Colorectal Cancer Cells by Regulating the Expression of Caspase-3 and Inhibits Autophagy
por: Zhang, Xinyi, et al.
Publicado: (2023)

Proteostasis is differentially modulated by inhibition of translation initiation or elongation
por: Clay, Khalyd J, et al.
Publicado: (2023)

Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
por: Wu, Yung-Hsuan, et al.
Publicado: (2022)

Competition between trans-translation and termination or elongation of translation
por: Asano, Krisana, et al.
Publicado: (2005)

Novel mutation in mitochondrial Elongation Factor EF-Tu associated to dysplastic leukoencephalopathy and defective mitochondrial DNA translation
por: Di Nottia, Michela, et al.
Publicado: (2017)

Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation
por: Koripella, Ravi Kiran, et al.
Publicado: (2020)

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins
por: Avolio, Rosario, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1v1u1o7m1irlj6c3qhajojbc9b