SDF‐1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up‐regulating FoxO1 via binding to CXCR4

Islet β cell dedifferentiation is one of the most important mechanisms in the occurrence and development of diabetes. We studied the possible effects of chemokine stromal cell‐derived factor‐1 (SDF‐1) in the dedifferentiation of islet β cells. It was noted that the number of dedifferentiated islet β...

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Detalles Bibliográficos
Autores principales: Chen, Xiang‐Yu, Shi, Ying‐Xin, Huang, Ya‐Ping, Ding, Min, Shen, Qi‐ling, Li, Chun‐Jun, Lin, Jing‐Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817121/
https://www.ncbi.nlm.nih.gov/pubmed/34935260
http://dx.doi.org/10.1111/jcmm.17110

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